Muscle Insulin Resistance in Aging (Mirage)

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to provide information regarding potential factors underlying metabolic dysfunction, insulin resistance, and loss of muscle mass in aging muscle.

Clinical Trial Description

Study Objectives: 1. To determine the effects of diet-induced weight loss with and without the addition of exercise on mitochondrial biogenesis and energetic capacity, cellular redox state and insulin resistance. 2. To determine the effects of diet-induced weight loss with and without the addition of exercise on intramyocellular lipid profiles. 3. To determine the effects of diet-induced weight loss with and without exercise on skeletal muscle proteins mediating a program of autophagy and either loss or maintenance of muscle mass. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02230839
Study type	Interventional
Source	AdventHealth Translational Research Institute
Contact
Status	Active, not recruiting
Phase	N/A
Start date	June 2014
Completion date	December 2024

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