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Insulin Resistance, Diabetes clinical trials

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NCT ID: NCT03511521 Terminated - Clinical trials for Insulin Resistance, Diabetes

Use of NPH Versus Basal Bolus Insulin for Steroid Induced Hyperglycemia

Start date: March 27, 2018
Phase: Phase 4
Study type: Interventional

Glucocorticoids are known to cause an increase in insulin resistance, leading to hyperglycemia, in both diabetic and non-diabetic patients. In both the inpatient and outpatient setting, steroids are used for their anti-inflammatory property to treat a variety of conditions. There is a paucity of information regarding the best way to treat steroid-induced hyperglycemia. In this study we will compare (1) the addition of NPH insulin, an intermediate-acting insulin, given at the time of steroid administration to the patient's standard basal/bolus insulin to (2) modification of the standard basal-bolus insulin regimen which will consist primarily increasing the prandial doses at lunch and supper in order to determine which regimen is superior for glycemic control.