Action of Caffeinated and Decaffeinated Espresso on Autonomic Function

Influence of Espresso on Heart Rate Variability Clinical Trial

Official title: Short-term Autonomic Effects of Caffeinated and Decaffeinated Espresso in Young Healthy Individuals

Status Terminated

Clinical Trial Summary

More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee.

In our study we aim to test the following hypotheses:

1. Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart.

2. Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease.

3. Caffeinated or decaffeinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Influence of Espresso on Heart Rate Variability

• NCT number: NCT00576030
• Study type: Interventional
• Source: Charite University, Berlin, Germany
• Status: Terminated
• Phase: N/A
• Start date: January 2007
• Completion date: October 2008