Inflammatory Response Clinical Trial
Official title:
Impact of Bulletproof Coffee on Metabolism, Inflammation and Cognitive Function
This study will determine whether acute ingestion of a high fat "Bulletproof Coffee" will lead to changes in plasma triglycerides, immune cell function, as well as cognitive function when compared to a black coffee.
Status | Recruiting |
Enrollment | 20 |
Est. completion date | December 31, 2020 |
Est. primary completion date | December 31, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 55 Years |
Eligibility |
Inclusion Criteria: - Must be over the age of 18 - Must drink between 1-4 cups of coffee per day (on average) - Must be able to tolerate lactose and dairy products - Have not been sick for the past 3 weeks (immune function) - Non smoker - Must be able to fast for 10-12 hours Exclusion Criteria: - If you are required to take corticosteroids (immune function) - Cannot understand or speak English - Individual has an auto-immune disease and requires medication - Individual is following a ketogenic diet - Individual has allergy or sensitivity to dairy, coffee or caffeine or coconut oil - Individual has hypertension |
Country | Name | City | State |
---|---|---|---|
Canada | University of British Columbia, Okanagan. | Kelowna | British Columbia |
Lead Sponsor | Collaborator |
---|---|
University of British Columbia |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Plasma triglycerides | Circulating triglycerides measured in mmol/L | Change over 3 hours following beverage consumption | |
Secondary | Cognitive function | Measures of cognitive function including Stroop test, digit substitution, and reaction time measured via computerized test battery. | Change over 3 hours following beverage consumption | |
Secondary | Immune Cell Activation | Assessment of activation markers on monocytes and neutrophils measured as median fluorescence intensity by flow cytometry. | Change over 3 hours following beverage consumption |
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