Effect of Oral Sildenafil Citrate on Improvement of Endometrial Thickness

Status Completed

Clinical Trial Summary

Clinical Trial Description

One hundred thirty women with unexplained infertility participated in a prospective clinical study. Patients were assigned at random to one of two groups. The first group (n=65) served as the study group and was given clomiphene citrate 50 mg (Tecnovula®, Techno Pharmaceuticals, Egypt) orally twice daily from the second day of their cycle through the seventh day and sildenafil (Respatio®, Pharma right group, Egypt) 20 mg tablets from the end of menstruation through ovulation. The second group (n=65) served as a control and received a placebo tablet in addition to the standard treatment of clomiphene citrate 50 mg (Tecnovula®). A transvaginal ultrasound was performed on all of the patients to assess ovulation, follicle count, and pregnancy. Consequences, including miscarriage, ectopic pregnancy, and multiple pregnancies, were monitored. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05846906
Study type	Interventional
Source	Beni-Suef University
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	October 1, 2021
Completion date	April 30, 2022

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