Infertility, Female Clinical Trial
Official title:
Effects of Treatment With Resveratrol on Oocyte and Embryo Quality in Patients Undergoing Assisted Reproductive Techniques( ART)
To evaluate the effects of a new nutraceutical formulation containing resveratrol (trademark GENANTE) on gamete quality in order to improve the reproductive process during ART.
The purpose of the study is to evaluate the effect of a new nutraceutical formulation
containing resveratrol (trademark Genante) on gamete quality in order to improve the
reproductive protocols during Assisted reproductive technology (ART) protocols.
The study is a randomized, single blind, parallel, comparative, experimental study during the
pre-treatment before in vitro fertilization-embryo transfer (IVF-ET). A total number of 100
patients will be enrolled: 50 patients with a pretreatment control group (control group) and
50 patients with experimental pretreatment study group (resveratrol group). Patients will be
assigned to groups during the recruitment phase in a randomized manner. In the control group,
the treatment will consist of taking 400 microg once a day of folic acid commonly suggested
as part of clinical practice, while in the Resveratrol Group, patients will receive one
tablet twice a day (two tablets/day) of Genante. It is specified that the pretreatment with
Genante includes folic acid in accordance with the clinical practice, 400 total microg per
day. Both treatments will last for 3 months before the IVF procedure.
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