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Ovarian Rejuvenation for Premature Ovarian Insufficiency and Poor Ovarian Response

Infertility, Female Clinical Trial

Official title:
Ovarian Rejuvenation Through Intra-ovarian Injection of Platelet Rich Plasma for Women With Premature Ovarian Insufficiency (POI) and Poor Ovarian Response (POR)

Clinical Trial Summary

The objective of this study is to perform a prospective randomized controlled trial seeking to characterize the effects of intra-ovarian injection of platelet rich plasma (PRP) on biomarkers of ovarian reserve as well as IVF outcomes in women with primary ovarian insufficiency (POI) and poor ovarian response (POR) who decline the use of an egg donor to establish a pregnancy.

Clinical Trial Description

Patients will be randomized to either receive the intra-ovarian PRP injection procedure or not. Regardless of randomization patients will be re-assessed at the same time points for ovarian reserve parameters. If antral follicles are detected at follow up, patients will undergo controlled ovarian hyperstimulation and a routine in vitro fertilization cycle as per protocol. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04163640
Study type Interventional
Source Reproductive Medicine Associates of New Jersey
Contact
Status Completed
Phase N/A
Start date February 24, 2020
Completion date July 21, 2023
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