Infertility, Female Clinical Trial
Official title:
A New Revolutionary 3-Injection- Protocol in Infertile Women With a Single Long Acting GnRH Antagonist in the Luteal Phase, a Bolus Gonadotropin Injection in the Early Follicular Phase and a Single Triggering Dose.
This is a prospective randomised study of the evaluation of the clinical IVF results after following a new revolutionary 3-Injection- Protocol for controlled ovarian stimulation in infertile women.
A randomized prospective study focusing on infertile women undergoing ovarian stimulation for
IVF, using Elonva (corifollitropin alfa) as part of two different stimulation protocols.
Women assigned to Protocol A receive a bolus late luteal dose of Degarelix, a new long acting
GnRH antagonist, a sole Elonva injection in the evening of day 3 of the cycle, followed by
the administration of a single dose of triggering agent (GnRH agonist or hCG a, according to
the individual response).
Women assigned to Protocol B are administered a single dose of Elonva (corifollitropin alfa)
on day 2 of the cycle, followed by daily GnRH antagonist doses, fixed on day 7 of the cycle.
Ovulation triggering is the same as in group A, with either GnRH agonist or hCG a,
accordingly.
Live Birth Rates are estimated for both groups of patients. The number of the formed
blastocysts in each group is measured, as well.
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