Reducing Nephrotoxicity of Vancomycin: A Prospective Study of Continuous Versus Intermittent Infusion of Vancomycin

Infections Requiring Prolonged Duration (>10 Days) of Vancomycin Clinical Trial

Official title: Reducing Nephrotoxicity of Vancomycin: A Prospective, Randomized Study of Continuous Versus Intermittent Infusion of Vancomycin

Status Recruiting

Clinical Trial Summary

This study is being carried out to find out whether there is reduction in vancomycin-induced kidney injury (nephrotoxicity) when vancomycin is given as intermittent versus continuous infusion.

This study will recruit 220 subjects from 2 hospitals over a period of 3 years.

Participants are invited if they have an infection that requires prolonged vancomycin therapy (> more than 10 days).

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

• Infections Requiring Prolonged Duration (>10 Days) of Vancomycin

• NCT number: NCT01720940
• Study type: Interventional
• Source: National University Hospital, Singapore
• Contact: Shire Yang Tan
• Phone: 97989001
• Email: shire_yang_tan@nuhs.edu.sg
• Status: Recruiting
• Phase: N/A
• Start date: October 2012
• Completion date: September 2015