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Infantile clinical trials

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NCT ID: NCT05328037 Completed - Diarrhea Clinical Trials

Study on the Association Between Vitamin C Deficiency and Diarrhea in Children

VITAL
Start date: April 25, 2022
Phase:
Study type: Observational

Diarrheal disease is the second leading cause of death in children under five, althought it is both preventable and treatable. The causative factors of diarrheal diseases vary a lot from region to region (bacteria, viruses, parasites). Diarrhea is one of the main causes of malnutrition in children under five years of age. Inversely, nutritional deficiency, particularly vitamin C deficiency, can be a risk factor for diarrhea. The main objective of this study is to assess the impact of vitamin C deficiency on diarrheal infection in children aged 2 to 5 years in countries with a high diarrheal rate. This pilot case-control study will be conducted in metropolitan France, Africa and South America. This question will be addressed by comparing vitamin C levels in children with diarrhea, regardless of the infectious agent, to levels in age- and sex-matched controls.

NCT ID: NCT04537494 Not yet recruiting - Colic Clinical Trials

PRobiotics for EVEry Newborn Trial

PREVENT
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare prevention (oral supplementation with the probiotic L. reuteri administered to every newborn within the first week of life for 12 weeks) with treatment-as-needed (supplementation with the probiotic L. reuteri after randomization, to infants who develop excessive cry/fuss up to 12 weeks of age). This is a single site pilot study to assess feasibility for a full trial.

NCT ID: NCT00689533 Recruiting - Infantile Clinical Trials

VEPTR Implantation to Treat Children With Early Onset Scoliosis Without Rib Abnormalities

Start date: January 2008
Phase: N/A
Study type: Observational

Primary Objective: To evaluate the use of unilateral or bilateral VEPTR devices, with or without expansion thoracoplasty, for preventing further progression of the Cobb angle, allowing for spinal growth and improving pulmonary function in the treatment of children with progressive scoliosis without rib abnormalities.

NCT ID: NCT00657748 Withdrawn - Canavan Disease Clinical Trials

Lithium and Acetate for Canavan Disease

Start date: September 2009
Phase: Phase 2
Study type: Interventional

The aim of this study is to determine whether oral supplementation with lithium and acetate may improve the biological and clinical prognosis in patients with Canavan Disease.