Clinical Trials Logo
  1. Home
  2. Infant Development
  3. NCT05945017

Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g

Infant Development Clinical Trial

Official title:
Probiotics and the Neurodevelopment in the Premature Infant <32 Weeks Gestational Age and <1500g

Clinical Trial Summary

Unicentric, quasi-experimental, cohort study to evaluate the effect of combining two probiotics (Bifidobacterium bifidum NCDO 2203 and Lactobacillus acidophilus NCDO 1748) in the neurodevelopment of preterm neonates below 32 weeks' gestation and a birthweight under 1,500 g. This probiotic combination has shown to be safe and beneficial in premature neonates in the prevention of NEC. The investigators hypothesised that this mixture would contribute to better neurodevelopmental outcomes of preterm neonates when assessed at 24 months corrected age. Additionally, neurodevelopment improved would be more relevant at 6 years of age, together with a better pattern of neuronal plasticity biomarkers. Secondarily, this mixture of probiotics could reduce NEC, LOS, intraventricular haemorrhage and neonatal mortality in accordance with previous studies.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05945017
Study type Interventional
Source Fundacion Clinic per a la Recerca Biomédica
Contact
Status Active, not recruiting
Phase N/A
Start date January 1, 2014
Completion date December 31, 2027
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05793112 - INF108F in Infants With Food Protein Induced Proctocolitis Phase 4
Recruiting NCT03828708 - Early Iron Exposure on the Gut Microbiota in Young Infants N/A
Recruiting NCT06018064 - Investigating Fit and Satisfaction of the Prone Positioner N/A
Not yet recruiting NCT06335524 - Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants N/A
Not yet recruiting NCT05039918 - Neonatal Experience of Social Touch N/A
Completed NCT01166867 - A Pilot Study Using Photo-plethysmographic (PPG) Camera
Completed NCT00791466 - Maternal Iodine Supplementation and Effects on Thyroid Function and Child Development N/A
Completed NCT03331276 - Growth and Safety Study of an Infant Formula for Healthy Term Infants N/A
Completed NCT05157633 - Oral Exploration of Objects and Food Diversification
Completed NCT05217186 - Associations Between Early Neonatal Neuroimaging, Hammersmith Infant Neurological Examination and General Movements
Recruiting NCT05006989 - Blueberry Intake and Infant Gut Health N/A
Completed NCT04901611 - Parental Touch Trial (Petal) N/A
Completed NCT03082313 - Movement-based Infant Intervention N/A
Recruiting NCT06053515 - Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication N/A
Completed NCT05394883 - The SPROUT (Pilot) Project N/A
Completed NCT03991949 - Evaluation of Preterm Infants Fed Post-Discharge Preterm Infant Formula N/A
Active, not recruiting NCT03851120 - Brain Probiotic and LC-PUFA Intervention for Optimum Early Life Phase 2
Completed NCT03662048 - Improving Infant Sleep Safety With the Electronic Health Record N/A
Active, not recruiting NCT04749888 - Impact of the Korea Early Childhood Home-visiting Intervention N/A
Recruiting NCT06230848 - Multisensory Early Oral Administration of Human Milk in Preterm Infants N/A