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Infant Development clinical trials

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NCT ID: NCT02069782 Active, not recruiting - Pregnancy Clinical Trials

Mother and Infant Home Visiting Program Evaluation

MIHOPE
Start date: October 2012
Phase: N/A
Study type: Interventional

MIHOPE is a multi-state study of home visiting programs authorized under the Maternal, Infant, and Early Childhood Home Visiting (MIECHV) program. The study is required by the federal Patient Protection and Affordable Care Act of 2010 (ACA), which created the MIECHV program. It is being conducted by MDRC under contract to the Administration for Children and Families within the US Department of Health and Human Services. In conducting the research, MDRC has subcontracted portions of the research to Mathematica Policy Research, Johns Hopkins University, Columbia University, University of Georgia, and James Bell Associates. MIHOPE is randomly assigned 4,229 families nationally to home visiting services or to a comparison group that will receive referrals to other services in the community. The study is seeking to include 88 local home visiting programs (sites) that are funded through MIECHV in approximately 12 states. Data will be collected from families, local home visiting programs, and state and federal administrative data systems to assess the effects of the programs on family outcomes and to learn more about how the programs are run. Sites included in the evaluation will be using one of four national service models (Nurse Family Partnership, Healthy Families America, Parents as Teachers, and Early Head Start-Home Visiting Option) that states have chosen for most of their MIECHV funding. MIHOPE will inform the federal government about the effectiveness of the MIECHV program in its first few years of operation, and it will provide information to help states develop and strengthen home visiting programs in the future. Research findings will be disseminated through a report to Congress in 2015; reports on program impacts, implementation, and on the relationship between program features and program impacts; journal articles; and practitioner briefs.

NCT ID: NCT02058225 Completed - Infant Development Clinical Trials

Developing Advanced MRI Methods for Detecting the Impact of Nutrients on Infant Brain Development

Start date: March 1, 2014
Phase: N/A
Study type: Observational

The purpose is to study the effect of infant nutrition on brain development, as measured using Magnetic Resonance (MR) techniques. The investigators will collect detailed information about the diet of each of the infants, and seek to correlate this information with multiple MR measurements, including structural imaging, diffusion imaging, and functional connectivity. The MR scans will be performed at birth and 3 months of age. Dietary information collected will include detailed food diaries describing the feeding habits of the infants, and food frequency questionnaires to characterize the diet of the mother.

NCT ID: NCT01947426 Completed - Inflammation Clinical Trials

Effect of Mother DHA Supplementation on Term Newborn.

Start date: April 2008
Phase: Phase 2/Phase 3
Study type: Interventional

In the present study, we evaluate the effect of the mother suplementación with DHA during the gestation and lactation on diverse aspects of the development of newborn. The effect on the oxidative stress, inflammatory signaling, bone turnover and piscomotor and visual development was studied. Women will in the sixth month of pregnancy, consume a diet balanced during last 3 months of pregnancy and the whole lactation. In addition the women will divide in two groups: one will receive a supplement of docosahexaenoic acid (DHA) to evaluate the effects on the development of the newborn child; whereas another group will receive a placebo. Different samples of blood of the mother and of mother milk will be taken and we will correlating her lipidic profile with the brain development of the newborn child, evaluated by different tests.

NCT ID: NCT01611649 Completed - Infant Development Clinical Trials

Effect of a Mix of Dairy Lipids and Plant Oils in Infant Formula on Omega-3 Fatty Acid in Red Blood Cells

REBECA
Start date: March 2012
Phase: Phase 2
Study type: Interventional

The objective of this study is to determine whether the use of a mix of dairy lipids and plant oils in infant formula can increase the sum of omega-3 fatty acids levels in membrane phospholipids of red blood cells (RBC) in 4 month-old infants compared with a formula containing only lipids of plant origin.

NCT ID: NCT01459848 Completed - Infant Development Clinical Trials

Baby Dvd Effects on Cortisol

Start date: January 2011
Phase: N/A
Study type: Interventional

The investigators will do an experiment where 9-12 month old infants are randomized to 30 minutes of block play or 30 minutes of watching a baby DVD.

NCT ID: NCT01373177 Completed - Infant Development Clinical Trials

Differences Between the Bayley-II and the Bayley-III in Very Preterm Infants at 2 Years

Start date: January 2011
Phase: N/A
Study type: Interventional

The objective of this randomized study is to test the hypothesis that scores on the Bayley Scales of Infant Development-III (Bayley-III) are higher than scores on the Bayley Scales of Infant Development-II (BSID-II) in the same group of infants who were born very preterm.

NCT ID: NCT01274299 Recruiting - Infant Development Clinical Trials

Measurements of Facial Dimensions in Infants and Toddlers 0-4 Years of Age

Start date: November 2010
Phase: N/A
Study type: Observational

Anthropometric data of infants' face will be obtained using special 3D scanners and software.

NCT ID: NCT01166867 Completed - Infant Development Clinical Trials

A Pilot Study Using Photo-plethysmographic (PPG) Camera

Start date: September 2009
Phase:
Study type: Observational

The researcher want to use video signals to monitor heart rate, respiration rate and oxygen saturation using Photo-plethysmography (PPG) as the underlying mechanism for the method: periodic changes in skin reflectance, induced by the cardio-vascular wave, are measured using light.

NCT ID: NCT00982462 Completed - Infant Development Clinical Trials

Effect of Long-Chain Polyunsaturated Fatty Acid Supplementation on Toddler Cognition

Start date: January 20, 2011
Phase: N/A
Study type: Interventional

The hypothesis to be examined is that dietary LCP-supplementation in the second and third years of life will improve cognitive and visual maturation in early childhood.

NCT ID: NCT00791466 Completed - Infant Development Clinical Trials

Maternal Iodine Supplementation and Effects on Thyroid Function and Child Development

MITCH
Start date: September 2008
Phase: N/A
Study type: Interventional

Rationale: In regions of severe endemic goiter, the adverse effects of in utero iodine deficiency on neuromotor development are well established: randomized controlled trials of iodine supplements given to iodine deficient mothers before pregnancy or during early pregnancy improve motor and cognitive performance of their offspring. However, the potential adverse effects of mild-to-moderate iodine deficiency during pregnancy are unclear. Inadequate thyroid function in the fetus and newborn are the likely cause of brain damage in iodine deficiency. Objective: To determine whether the daily oral administration of 200 µg iodine to pregnant women in areas of mild-to-moderate iodine deficiency improves maternal and newborn thyroid function, pregnancy outcome, birth weight, infant growth and cognitive performance. Study design: Double-blind randomized controlled multicentre trial. Study population: Pregnant women (18-40 years) presenting at the clinic for their first prenatal visit will be recruited at two research sites, namely St. Martha's hospital in Bangalore, India and Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. At each site, 400 women will be recruited. Intervention: Half of the women will be randomized to iodine treatment (200 µg per day) and the other half to placebo throughout pregnancy. Main study parameters/endpoints: Differences between group means in indicators of thyroid function, birth outcome, urinary iodine, breast milk iodine, infant growth, and psychomotor development.