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Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients

Induction of Labor Affected Fetus / Newborn Clinical Trial

Official title:
Propranolol Versus Placebo for Induction of Labor in Nulliparous Patients: a Double-blind Randomized Controlled Trial

Clinical Trial Summary

A randomized, prospective trial will be offered to women admitted to the labor floors at Mount Sinai Medical Center for labor induction.

Clinical Trial Description

Induction of labor is a common obstetric procedure, which is performed to provoke the onset of labor and lead to delivery of the fetus. While some early studies suggested a possible increased rate of cesarean with induction of labor, more recent meta-analyses have shown that induction does not influence this rate. There is data from small randomized studies that demonstrates the effectiveness of propranolol, a non-selective beta-blocker, for induction of labor. This literature suggests a decrease in the amount of time to delivery and a possible reduction in cesarean section rates when propranolol is used in conjunction with oxytocin for induction of labor compared to oxytocin alone. ;

Study Design

Related Conditions & MeSH terms

  • Induction of Labor Affected Fetus / Newborn
Clinical Trial Details
NCT number NCT03348683
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact
Status Completed
Phase Phase 2
Start date December 11, 2017
Completion date December 11, 2018
View Details
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