Clinical Trials Logo

Clinical Trial Summary

Indocyanine green NIR imaging is valuable for lymph node dissection in D3 radical surgery for rectal cancer. It can guide the intraoperative improvement of lymph node dissection based on the preservation of LCA and peripheral autonomic nerves of IMA. This not only reduces the occurrence of postoperative complications and promotes rapid postoperative recovery, but also provides a more precise and individualized comprehensive treatment plan for patients after surgery. In addition,this trial also demonstrated that ICG is safe and feasible for use in rectal cancer


Clinical Trial Description

The pathological data of 96 patients with rectal cancer from September 2020 - July 2022 were collected from the First Hospital of Qinhuangdao City.In 51 of these patients, ICG was injected preoperatively via anoscope or anal dilator in the mucosal layer around the tumor, and surgical treatment was performed after visualization. The surgical approach was performed by laparoscopic radical rectal cancer with an intermediate approach step.The IMA root is treated with low ligation of the IMA, while lymph node dissection is performed while preserving the autonomic nerves around the IMA. The other 45 patients were not injected with ICG, and the procedure was performed as before.The occurrence of postoperative complications was recorded, and the detection of lymph nodes was also compared between the two groups, as well as the intraoperative situation and postoperative recovery. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05517681
Study type Interventional
Source The First Hospital of Qinhuangdao
Contact
Status Completed
Phase N/A
Start date September 7, 2020
Completion date July 10, 2022

See also
  Status Clinical Trial Phase
Recruiting NCT04615806 - The Value of Lymph Node Dissection of Indocyanine Green-guided Near-infrared Fluorescent Imaging in Esophagectomy N/A
Completed NCT03050879 - Indocyanine Green Tracer Using in Laparoscopic Gastrectomy With Lymph Node Dissection Phase 2
Recruiting NCT06033794 - Applications of Fluorescence Imaging Guided Lymph Node Dissection and Fluorescence Angiography of Inferior Mesenteric Artery Assisted Left Colic Artery Preservation N/A
Completed NCT01886066 - Accuracy of Sentinel Lymph Node Biopsy in Nodal Staging of High Risk Endometrial Cancer N/A
Not yet recruiting NCT06302985 - Atomized Inhalation ICG for Treatment of Congenital Lung Malformations N/A
Recruiting NCT04514289 - To Assess and Compare the Performance Two Approach for Sentinel Lymph Node (SNLD) Biopsy for Endometrial Cancer
Not yet recruiting NCT04973475 - Indocyanine Green Tracer Using in Laparoscopic Distal Gastrectomy for Early Gastric Cancer Phase 2
Recruiting NCT04908826 - Comparison of Icg's Route of Administration During Laparoscopic Cholecystectomy N/A
Active, not recruiting NCT06313385 - Investigating the Impact of Indocyanine Green Titration on Fluorescent Intensity in Free Flap : An Exploration of Alternative Indicators N/A
Recruiting NCT06288750 - Protective Effect of Indocyanine Green Fluorescence Imaging Technology on Parathyroid Glands During Total Thyroidectomy N/A
Active, not recruiting NCT04219332 - Randomized Controlled Trial on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection Phase 3
Completed NCT04570800 - One Way to Diagnose Hepatic Insufficiency the First Postoperative Day After Resection: Prospective Cohort Study
Recruiting NCT04207489 - Endoscopic Submucosal Injection of Indocyanine Green Before Laparoscopic Radical Resection for Colorectal Cancer