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Incisional Hernia clinical trials

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NCT ID: NCT06178965 Active, not recruiting - Incisional Hernia Clinical Trials

Incisional Hernia Repair by Abdominal Wall Component Release With Contemporary Onlay Mesh Fixation

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

There is a great expansion in the presentation of complex incisional hernia defects. Primary closure for most cases is impossible with a high rate of recurrence. Component separation provides an autologous repair of the defect but still has considerable recurrence rate. Reinforcement of component separation provides a more strength full repair and may be less recurrence.

NCT ID: NCT04626336 Active, not recruiting - Hernia Clinical Trials

Post-operative Hernias After Radical Cystectomy

Start date: January 30, 2010
Phase:
Study type: Observational

Post-operative hernias after cystectomy are frequent (our review of the literature with meta-analysis found an incidence of evisceration at 5%, median eventrations at 8% and peristomal hernias at 14%). These represent a non-negligible and partially morbidity. avoidable, subject to proper assessment of personal and surgical risk factors

NCT ID: NCT04311788 Active, not recruiting - Incisional Hernia Clinical Trials

Preemer Trial - Prophylactic Mesh Versus no Mesh in the Midline Emergency Laparotomy Closure for Prevention of Incisional Hernia: a Multi Center, Double-blind, Randomized Controlled Trial

Start date: April 27, 2020
Phase: N/A
Study type: Interventional

244 patients, who have an emergency midline laparotomy for any gastrointestinal reason, will be randomized in a 1:1 ratio either to mesh group with a retrorectus prophylactic self-gripping mesh or to control group with 4:1 small stitch closure by continuous monofilament suture. They will be followed up at 30 days, 2 and 5 years to detect the incidence of incisional hernia.

NCT ID: NCT03445936 Active, not recruiting - Rectum Cancer Clinical Trials

PRELOOP Trial: Synthetic Versus Biological Mesh for Prevention of Incisional Hernia After Loop-ileostomy Closure

Start date: February 13, 2018
Phase: N/A
Study type: Interventional

This study compares a synthetic mesh and biological implant in prevention of incisional hernia after loop-ileostomy closure.

NCT ID: NCT03390764 Active, not recruiting - Quality of Life Clinical Trials

Hernia After Colorectal Cancer Surgery

Rein4CeTo1
Start date: October 16, 2017
Phase: N/A
Study type: Interventional

Defects in the abdominal wall (incisional hernia) is a frequent negative outcome after surgery. Reinforcing the incision with mesh seem to lower the incidence but in surgery that includes bowel resection a simple alternative, cheaper and less prone to infection than a synthetic mesh, would be of interest. The primary aim of this multicentre randomized controlled trial is to compare the incisional hernia incidence one year after planned colorectal cancer surgery performed through a midline incision which is closed either by a standardized small stitch 4:1 technique (the incision is closed with the use of suture of 4 times the length of the incision) or with the same technique plus a reinforced tension-line suture (a suture is applied in the fibrous tissue parallel to the incision which is then embraced by the 4:1 suture when the incision is closed). A difference in incisional hernia of 15% (20% without and 5% with reinforced tension-line suture) is assumed. Secondary aims are to evaluate incidences of wound dehiscence, other wound complications and incisional hernia after 3 years. Furthermore we aim to evaluate patient satisfaction and quality of life.

NCT ID: NCT03380312 Active, not recruiting - Hernia, Incisional Clinical Trials

MRI Imaging of Ipsilateral Retromuscular Access

Start date: September 26, 2017
Phase:
Study type: Observational

The aim of this study is to measure the mesh shrinkage and the visualization of the mesh with MRI scan at 1 month and 13 months after robot assisted retromuscular incisional hernia repair with ipsilateral access and the use of the visible CICAT mesh (Dynamesh®) for defect repair. The investigators also want to measure the volume of the rectus muscles and the change between 1 and 13 months.

NCT ID: NCT03324854 Active, not recruiting - Hernia, Ventral Clinical Trials

Use of Mosquito Net Mesh for Ventral Hernia Repair

Start date: July 1, 2016
Phase: N/A
Study type: Interventional

It´s a pilot study, randomized, realized in the Central Hospital "Dr. Ignacio Morones Prieto", SLP, Mexico. Hypothesis: The polyethylene mesh is secure in open ventral repair.

NCT ID: NCT02542085 Active, not recruiting - Incisional Hernia Clinical Trials

Comparison of Hybrid and Laparoscopic Incisional Hernia Repair

Start date: November 2012
Phase: N/A
Study type: Interventional

Study is a prospective, multicenter, randomized trial evaluating two laparoscopic incisional hernia repair methods: basic laparoscopic mesh repair (lap.) and a hybrid repair (laparoscopic mesh and fascial suturation). Patients are recruited prospectively from 10 Finnish Hospitals (Oulu, Jorvi, Hyvinkää, Kotka, Seinäjoki, Valkeakoski, Lahti, Kuopio, Kokkola, Loimaa). Patients are randomized to operative groups (lap. vs hybrid). Follow-up visits are scheduled at 1- and 12-month after surgery. Patients are evaluated for their clinical status and an ultrasound scan is performed. QoL-questionnaire and pain score (VAS) are reported. The primary end-points: - clinically and/or radiologically detected seroma in 1 month control - clinically and/or radiologically detected recurrent hernia in 1 year control The secondary end-points: - peri-and postoperative outcomes/ complications, morbidity, mortality - duration of hospital stay - pain scale (VAS) - Quality of Life (SF/Rand36)

NCT ID: NCT02328352 Active, not recruiting - Incisional Hernia Clinical Trials

"BP as a New Device for Surgery and Solid Cancer and Hematopoietic System Tumors Treatment. Effects of BP Implantation"

DM159
Start date: October 2010
Phase: Phase 1/Phase 2
Study type: Interventional

Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias in humans, in laparotomic procedures and as a new device for the treatment of solid cancer and hematopoietic system tumors. The experimentation on this new material, preliminary conducted on breed female rabbit New Zeeland, will be applicable to human, if the results in terms of toxicity and durability will be comfortable.

NCT ID: NCT02137018 Active, not recruiting - Incisional Hernia Clinical Trials

"Nanotechnologies Applied to General Surgery and Emergency Surgery: Buckypaper as a New Fixing Method for Prosthetic Materials for the Treatment of Hernia and Incisional Hernia in Laparotomy and Laparoscopic

36P
Start date: March 2013
Phase: Phase 1/Phase 2
Study type: Interventional

"Nanotechnologies applied to General Surgery and Emergency Surgery: The Buckypaper as a new fixing method for prosthetic materials in the treatment of abdominal wall hernias, diaphragmatic hernias, diaphragmatic rupture, incisional hernia and abdominal wall disaster in laparotomy procedure and laparoscopic procedures". Experimentation on breed pig Lantrace ANIMAL MODEL.