Big Data Analysis of the Use of bIomarkers Concentration

Status Completed

Clinical Trial Summary

The investigators conducted a retrospective analysis of all measured concentrations performed in a large subset of laboratories located in the French Brittany from February 2010 the 17th to August 2015 the 30th, in adults over 20 years old.

The investigators are aimed at studying physicians' use and eventually misuse of biomarkers dosage and the characteristics of a broad population based on some biomarkers concentrations.

Clinical Trial Description

The rUBIDIuM study is a retrospective analysis that included all tests (but not including DNA analysis or HIV tests) performed in a large subset of laboratories located in the French Brittany from February 2010 the 17th to August 2015 the 30th. The area of study covers most of the Ille-et-Vilaine and a part of the Côtes d'Armor department in Brittany. The respective surface of these departments is 6775 and 6878 km2. All labs belong to the Biorance Laboratory group (consortium of 33 labs, Biorance Laboratoires Réunis) and are equipped with Roche Diagnostics instruments (Elecsys2010® analyzer, Roche diagnostics, Meylan, France).

The main objectives are to study physicians' use and eventually misuse of biomarkers dosage and the characteristics of this broad population based on some biomarkers concentrations.

For all adult patients >20y that came to a participating lab during the study period, the investigators collected the following information: demographics data, data about the prescription (date of order, list of analysis recommended, the date of blood collection and analysis), about the prescribers and the results of the analyses. After a de-identifying process, data were aggregated.

the initial analyses will 1) examine the biological tests (number, types…) ordered in a large cohort of patients, in the total population and the subgroups based on gender, age, time period, kind of lab and physicians' specialty, 2) examine the results/concentration of the analyses: blood chemistry, creatinin concentration, cardiac enzymes, natriuretic peptides, INR, lipid profile, hemogram… ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03254472
Study type	Observational
Source	Hospital Avicenne
Contact
Status	Completed
Phase	N/A
Start date	February 17, 2010
Completion date	September 10, 2015

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03688542` - Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module	N/A
Completed	`NCT02545257` - Development of a Coordinated, Community-Based Medication Management Model for Home-Dwelling Aged in Primary Care	N/A
Completed	`NCT03655405` - Randomised, Controlled Trial of an Individual Deprescribing Intervention for Nursing Homes Residents	N/A
Completed	`NCT02052505` - Reducing Inappropriate Prescribing for Psychiatric Patients Using Nurse-led Medication Reviews	N/A
Recruiting	`NCT06437444` - Asthma Crisis in Paediatrics: Impact of a Care Pathway in Primary and Hospital Care	N/A
Active, not recruiting	`NCT04022850` - De-implementation of Low-value Pharmacological Prescriptions	N/A
Completed	`NCT04294901` - Engaging Patients to Promote Deprescribing	N/A
Recruiting	`NCT03501108` - Discontinuation of Long-term Medications in Older People Entering Nursing Home Care	N/A
Enrolling by invitation	`NCT03689049` - SPIDER: A Research & QI Collaboration Supporting Practices in Improving Care for Complex Elderly Patients	N/A
Completed	`NCT02435290` - Enhancement of the Prediction of Chemotherapy Prescribing Errors for Oncology Patients	N/A
Completed	`NCT03539276` - An Intervention to Reduce Inappropriate Medications in Long-term Care Residents With Severe Dementia	N/A
Active, not recruiting	`NCT02744963` - Carefully seLected and Easily Accessible at No Charge Medications	N/A
Recruiting	`NCT05875623` - Impact of Medications Review on Potentially Inappropriate Medications and Clinical Outcomes Among Hospitalized Older Adults	N/A
Completed	`NCT04586595` - A Randomised Pilot Study of the REVISiT Intervention	N/A
Completed	`NCT03245879` - Antibiotic Stewardship in Small Hospitals	N/A
Not yet recruiting	`NCT06129474` - Deprescribing Inappropriate Proton Pump Inhibitors	N/A
Completed	`NCT06209827` - Effectiveness of a Community Intervention in the Chronic Use of Benzodiazepines: (BENZOSTOPJUNTOS)	N/A
Recruiting	`NCT04028583` - Tool for Inappropriate Prescription Evaluation: The TaIPE Study	N/A
Completed	`NCT05454644` - Effectiveness of a Person-centred Prescription Model at the End of Life	N/A
Completed	`NCT02918643` - Using a Mobile Application as a Support at the Prescription of Appropriate Medications for Elderly	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Big Data Analysis of the Use of bIomarkers Concentration — rUBIDIuM

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms