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In Vitro Fertilization clinical trials

View clinical trials related to In Vitro Fertilization.

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NCT ID: NCT00702806 Completed - Infertility Clinical Trials

Investigate Dose of Org 36286 to Initiate Multiple Follicular Growth in a Controlled Ovarian Hyperstimulation Protocol for IVF or IVF/ICSI (P07015)

Start date: July 1, 2001
Phase: Phase 2
Study type: Interventional

The primary objective of this trial was to investigate the appropriate dose of a single injection of Org 36286 to initiate multifollicular growth for the first seven days in a controlled ovarian hyperstimulation (COH) protocol for IVF and IVF/ICSI. After seven days, participants were converted to treatment with Puregon® 150 IU and administration of the GnRH antagonist Orgalutran® to finalize the stimulation cycle. Secondary objectives were the safety (including the absence of antibody formation) and the direct effects of Org 36286 on reproductive functions (steroidogenesis, oocyte maturation, embryo quality and implantation).

NCT ID: NCT00702546 Completed - Clinical trials for In Vitro Fertilization

Follow-up Protocol on the Outcome of Frozen-thawed Embryo Transfer Cycles From Clinical Trial P05690 (P05711)

Start date: December 2006
Phase:
Study type: Observational

Clinical trial objective is to collect the outcome of Frozen-Thawed Embryo Transfer (FTET) cycles performed after the embryos are cryopreserved in the base study P05690 in order to estimate the cumulative pregnancy rate for each treatment group.

NCT ID: NCT00702351 Completed - Clinical trials for In Vitro Fertilization

A Trial of Single Dose Corifollitropin Alfa's Ability to Induce Multiple Follicular Growth During the First Week of Controlled Ovarian Stimulation for IVF or ICSI (38833)(P05788)

Realize
Start date: December 9, 2005
Phase: Phase 2
Study type: Interventional

To evaluate the induction of multiple follicular growth after single dose administration of 100 μg or 150 μg Org 36286 in a long protocol of GnRH agonist.

NCT ID: NCT00702273 Completed - Clinical trials for In Vitro Fertilization

Follow-up Study of Frozen-thawed Embryo Transfer (FTET) Cycles After Cryopreservation of Embryos in Clinical Trial P05787 (P05716)

Start date: April 19, 2006
Phase:
Study type: Observational

To collect the outcome of frozen-thawed embryo transfer cycles after the embryos are cryopreserved up to at least 1 year in Trial P05787 (NCT00696800), in order to estimate the cumulative pregnancy rate for each treatment group.

NCT ID: NCT00696878 Completed - Clinical trials for In Vitro Fertilization

Corifollitropin Alfa in Participants Undergoing Repeated Controlled Ovarian Stimulation (COS) Cycles Using a Multiple Dose Gonadatropin Releasing Hormone (GnRH) Antagonist Protocol (Study 38825)(P05714)

Trust
Start date: September 26, 2006
Phase: Phase 3
Study type: Interventional

The objective of the trial is to assess the non-immunogenicity and safety of corifollitropin alfa (also known as Org 36286, SCH 900962 and MK-8962) in participants undergoing repeated COS cycles using a multiple dose GnRH antagonist protocol.

NCT ID: NCT00696800 Completed - Clinical trials for In Vitro Fertilization

A Study to Investigate the Efficacy and Safety of a Single Injection of Corifollitropin Alfa (Organon 36286) for Ovarian Stimulation Using Daily Recombinant Follicle Stimulating Hormone (FSH) as Reference (P05787)

Start date: June 27, 2006
Phase: Phase 3
Study type: Interventional

To investigate the efficacy and safety of a single injection of 150 μg Corifollitropin Alfa (Organon 36286) to induce multifollicular development for controlled ovarian stimulation using daily recombinant FSH (recFSH) as a reference. The primary hypothesis is that a single injection of Corifollitropin Alfa is non-inferior to daily treatment with recFSH in initiating multifollicular growth.

NCT ID: NCT00682071 Completed - Infertility Clinical Trials

Ultrasound Guided Embryo Transfer: Abdominal Versus Transvaginal, a RCT

Start date: August 2003
Phase: N/A
Study type: Observational

Ultrasound (US) guided embryo transfer (ET) appears to improve pregnancy outcomes in IVF-ET. Most reports are done using a transabdominal (TAS) approach, in contrast to a transvaginal ultrasound (TVS) which does not require a full bladder. We sought to determine if either approach was better with respect to clinical outcomes.

NCT ID: NCT00593671 Completed - Clinical trials for In Vitro Fertilization

Preimplantation Genetic Screening in Women Over 35 Year

Start date: June 2002
Phase: N/A
Study type: Interventional

In view of insufficient evidence to routinely use Preimplantation Genetic Screening (PGS) to improve success rates after IVF, we test the hypothesis that patients with advanced maternal age (AMA) have a higher implantation rate (IR) after embryo transfer (ET) of chromosomally normal embryos following PGS compared to patients who had an ET without PGS. In a randomized controlled trial (RCT) in patients with AMA (≥ 35 years), the clinical IR per embryo transferred will be compared after ET on day 5 or 6 between the PGS group (embryo biopsy and analysis of chromosomes 13, 16, 18, 21, 22, X and Y) and the control group without PGS.

NCT ID: NCT00557687 Completed - Clinical trials for In Vitro Fertilization

Prediction of Ovarian Response

Start date: May 2005
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate if there is an association between the endocrine and ultrasonographic markers of ovarian reserve and the IVF outcome and to determine which markers contribute to the prediction of poor response in IVF.

NCT ID: NCT00553293 Completed - Infertility Clinical Trials

Nordic Luveris Study

Start date: August 2003
Phase: Phase 4
Study type: Interventional

To study whether addition of human LH hormone (Luveris) during the final days of stimulation with recombinant FSH (Gonal-f) for controlled ovarian stimulation will be of benefit for patients undergoing in vitro fertilisation.