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Exposure to General Anaesthesia in Infancy and Neurocognitive Development — EGAIN  

Impaired Cognition Clinical Trial

Official title:
Prospective Cohort Study of Effects of Exposure to General Anaesthesia in Infancy on Neurocognitive Development

Clinical Trial Summary

This prospective cohort study aims to determine if apparently healthy children with no significant co-morbidities who undergo general anaesthesia for minor surgery before 15 months of age will develop measurable deficits in neurocognitive development compared to apparently healthy children with no significant co-morbidities who do not undergo general anaesthesia or surgery.

Clinical Trial Description

We hypothesize that healthy children exposed to general anaesthesia for minor surgery before 15 months of age will have significantly lower neurocognitive scores at 6,18, 24 and 36 months of age compared with age, and gender matched healthy children from the GUSTO cohort without prior exposure to general anaesthesia or surgery. (GUSTO: Growing Up Towards Healthy Outcomes in Singapore: a prospective longitudinal study providing normative data from the local population). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02182817
Study type Observational
Source KK Women's and Children's Hospital
Contact
Status Active, not recruiting
Phase
Start date November 2013
Completion date December 2021
View Details
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