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Immunological Disease clinical trials

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NCT ID: NCT05780099 Recruiting - Clinical trials for Cardiovascular Diseases

Prospective Observational Study to Characterize Patients Treated at Internal Medicine Clinics

MED-Cli
Start date: June 24, 2022
Phase:
Study type: Observational

Patients referred to internal medicine wards are becoming increasingly complex and fragile. Despite deep knowledge of their specific disorders, steps are required to improve overall management of their acute and chronic conditions. The main objective of the study is to identify demographic, clinical, laboratory and radiological markers of disease severity and activity in patients with diseases treated at general medicine wards (respiratory disease, immune-mediated disease, sepsis, metabolic disease, rare disease, frailty, pregnancy pathology) in order to improve their diagnosis, monitoring and treatment processes.

NCT ID: NCT04784364 Recruiting - Autoimmune Diseases Clinical Trials

Biologics And Clinical Immunology Cohort at Sinai

BACICS
Start date: March 3, 2021
Phase:
Study type: Observational [Patient Registry]

The study team plans to establish a bioregistry of patients receiving biologic therapy as part of their standard treatment at the Mount Sinai Therapeutic Infusion Center and affiliated practices. The study team will to apply state-of-the-art approaches to assessing and predicting immunological and clinical responses associated with these standards and prescribed treatments. The approach is twofold. The first component is to establish a robust and flexible biorepository and database that includes demographic, immunologic, exposure and clinical records, and can facilitate research across disciplines, and across other registries affiliated with Mount Sinai. The second component is to address specific key research questions focused on using novel diagnostics to increase the effectiveness of biologic treatment. Most patients will be recruited from the Mount Sinai Therapeutic Infusion Center (TIC), although others receiving infusions elsewhere or at home will be recruited from outpatient Sinai affiliated clinical practices.