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Immediate Implant Placement clinical trials

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NCT ID: NCT06246253 Not yet recruiting - Clinical trials for Immediate Implant Placement

Bone Formed Labial to the Implant in Relation to the Horizontal Gap Dimension in Immediate Implant Placement.

Start date: June 1, 2024
Phase:
Study type: Observational

Palate implant placement in extraction sockets, with a minimum of 2 mm between the implant and the inner side of the facial socket wall, has been advised as a step towards a 3D restorative-driven posture. The buccal gap left by this palatal location is identified by the term "jumping gap" or "jumping distance," which describes the capacity of bone to fill the void and bridge the horizontal gap. The gap is made up of a vertical and horizontal component. Significantly, this gap denotes the future buccal bone that will directly contribute to the buccal contour and impact the soft tissue levels, thus influencing the implant's final appearance. Consequently, it is now considered desirable to have a bigger horizontal gap since more newly created buccal bone is predicted to occur in areas with larger horizontal gaps.

NCT ID: NCT06207565 Not yet recruiting - Clinical trials for Immediate Implant Placement

Immediate Implant Placement Utilizing Vestibular Flap Versus Single Flap Approach With Bone Graft

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Due to the evolution of esthetic implant dentistry and tissue regeneration (hard and soft tissue), flap design plays a crucial role in the maintenance and regeneration of the marginal soft tissue and interdental papillae around dental implants. The present study aims to compare soft and hard tissue changes following immediate implant placement with ridge augmentation using the vestibular flap versus single flap approach.

NCT ID: NCT06038695 Withdrawn - Tooth Extraction Clinical Trials

Immediate Implant Placement Using Volume-Stable Collagen Matrix Combined With rhPDGF-BB

Start date: May 2025
Phase: N/A
Study type: Interventional

The goal of this study is to test a volume-stable collagen matrix in combination with recombinant human platelet-derived growth factor-BB, specifically in patients who have an immediate implant placement for teeth #5-#12. The main question this study aims to answer is does the recombinant human platelet-derived growth factor-BB accelerate the formation of blood vessels and augment tissue volume around the immediate implant. Participants will be asked to undergo immediate implant placement using volume-stable collagen matrix in combination with recombinant human platelet-derived growth factor-BB, as well as attend 11 study visits over the course of 1.25 years.

NCT ID: NCT05990283 Completed - Clinical trials for Immediate Implant Placement

Socket Shield Technique and Guided Bone Regeneration

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

Among the individuals who applied to the Department of Periodontology, Faculty of Dentistry, Health Sciences University between 2019 and 2021, patients with an unrestorable tooth in the maxillary esthetic region and required implant placement were included in this randomized clinical trial. Before implant surgery, patients were randomized into socket shield technique and guided bone regeneration groups. While the buccal gap was untreated in the socket shield group, a xenograft, and membrane were applied in the regeneration group. Peri-implant pocket depth, modified plaque index, modified bleeding index, keratinized mucosa width, and mucosal thickness were recorded at the permanent restoration and the postoperative first year. Horizontal bone level and vertical bone level were assessed with cone beam computed tomography images taken before the surgery and one year after prosthesis insertion. The pink esthetic score was evaluated with intraoral photographs taken before the surgical procedure and first-year follow-up.

NCT ID: NCT05880771 Enrolling by invitation - Clinical trials for Immediate Implant Placement

Immediate Implant Placement: a Clinical and Radiographic Study on Hard and Soft Tissues Retraction at One Year.

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

This project consists of placing dental implants at extraction sites. Bone drilling and implant placement are performed using the flapless method with the use of a surgical guide allowing guided surgery. After implant placement, temporary teeth are immediately made and placed on the implants to guide the gingival contour. Bone and soft tissue retraction at the implanted sites are measured radiographically and digitally using surface scan superimposition over a 12-month period.

NCT ID: NCT05670067 Active, not recruiting - Clinical trials for Immediate Implant Placement

Alveolar Ridge and Soft Tissue Augmentation Using Graft From the Maxillary Tuberosity

Start date: October 30, 2021
Phase: N/A
Study type: Interventional

In the study immediate implant is placed in the anterior region with autogenous bone grafting from the maxillary tuberosity in one group and in the other group immediate implant is placed with xenograft .IN both groups soft tissue grafting is done using connective tissue assessment of buccal bone thickness and soft tissue will be done 6 months post operative

NCT ID: NCT05436158 Recruiting - Clinical trials for Immediate Implant Placement

The Use of a New Safe Angle Position for Implant Placement in the Anterior Region.

Start date: May 1, 2022
Phase:
Study type: Observational

There is an angle between the intersection of the incisal long axis perpendicular to the palate or the occlusal plane, and the long axis of the root. When this relation is shifted more palatal, where the incisal plane line will be at the cingulum position or slightly palatal to it, it is named the safe angle position. The more palatal relocation to the cingulum is performed according to the availability of palatal bone, the occlusion with the opposing dentition, the type of the restoration (screw vs cemented). The possibility of having a specific safe angle to place implants opens new interesting perspectives for immediate placement of dental implants. The aim of the present study was to demonstrate how immediate implants in the safe angle position can be predictably achieve proper implant positioning, better esthetics and emergence profile as well as less stresses on the implant.

NCT ID: NCT05330702 Enrolling by invitation - Tooth Extraction Clinical Trials

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

Start date: January 17, 2023
Phase: N/A
Study type: Interventional

Mid-facial recession following immediate implant placement (IIP) in the place of a tooth poses a significant challenge for clinicians to treat. Emerging evidence shows that connective tissue graft (CTG) augmentation may mitigate the remodeling of the buccal bone crest (i.e., bone within the gum that supports the tooth), and lessen the soft tissue recession. A recent systemic review suggested a supplemental CTG grafting to IIP as a standard of care, especially for cases that have a high esthetic risk, specifically with a thin gingival biotype (i.e., thin gum tissue) and a thin buccal bone plate. The alternative option to augment the facial contour is the xenogeneic volume-stable collagen matrix (VCMX), which favors avoiding morbidity but hasn't been thoroughly investigated on IIP. Despite that IIP has attracted considerable scientific interest, the dynamic changes of the bone crest and soft tissue, especially during the early healing stage (<3 months following IIP), are little known. Recently, an ultrasonography protocol has been validated for its diagnostic value in dental implant research. High-frequency B-mode imaging and color flow and power Doppler are implemented to display the spatial relation of anatomic landmarks of peri-implant tissues and to visualize the flow velocity and blood volume, respectively. It provides a valuable real-time diagnostic tool to evaluate hard and soft tissue remodeling and tissue perfusion changes during the early healing stage around IIP, comparing CTG and VCMX grafting. Hence, the purpose of this three-arm RCT is to compare the clinical efficacy and longitudinal remodeling of hard and soft tissue around IIP among CTG, VCMX, and control (without soft tissue augmentation) group. This will be the first evidence of the longitudinal tissue changes around immediate implant, and the first RCT comparing the clinical efficacy and esthetic outcome of xenogenic soft tissue substitute (i.e., from the non-living bone of another species) to the gold standard approach (CTG) on the immediate implants.

NCT ID: NCT04992416 Completed - Clinical trials for Immediate Implant Placement

Immediately Placed Implants Using Simvastatin and Autogenous Tooth Graft Combination in Periodontally Compromised Sites

Start date: September 2, 2021
Phase: N/A
Study type: Interventional

Recently, autogenous tooth graft (ATG) made from compromised teeth was applied in bone defects and resulted in a good clinical efficacy.(6) Moreover, it is more accepted by patients to use extracted teeth as a bone graft material, especially in the case of immediate implant placement. Simvastatin (SMV), known as a 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor, is widely used to decrease serum cholesterol because of its safe and effective treatment. Apart from cholesterol-lowering effects, SMV is also found to promote osteogenic differentiation of bone marrow stem cells (BMSCs), suppress osteoclastic differentiation in bone tissue and promotes osseointegration around implants in animal studies. SMV is reported to enhance autophagy and alleviates the ROS of BMSCs in the osseointegration of implants. The present study will be carried out to evaluate the effect of SMV combined with ATG on bone formation around immediately placed dental implants.

NCT ID: NCT04803500 Completed - Clinical trials for Alveolar Bone Resorption

Simvastatin Around Immediate Implant

Start date: April 2, 2015
Phase: Phase 2
Study type: Interventional

The study evaluated the effect of local application of simvastatin around immediate implant on the amount of gap fill, ridge dimensional alterations and bone density in humans.