Idiopathic Parkinson's Disease Clinical Trial
Official title:
Efficacy of Acupuncture and Bee Venom Acupuncture on Patients With Idiopathic Parkinson's Disease
The aim of this study is to evaluate the efficacy of acupuncture and bee venom acupuncture (BVA) for idiopathic Parkinson's disease (IPD) through a sham-controlled trial and investigate whether there is sustainability of treatments effects by follow-up assessments after the end of the treatment.
A total of 90 patients with idiopathic Parkinson's disease (IPD) who have been on a stable
dose of anti-parkinsonian medication for at least one month with two or more symptoms among
tremor, rigidity, postural instability, and bradykinesia will be included in this study.
Participants will be randomly assigned to the study, the control, or the waiting group
(2:2:1).
Initial assessment will be performed with the Unified Parkinson's Disease Rating Scale
(UPDRS) parts II and III, the Parkinson's Disease Quality of Life Questionnaire (PDQL), the
Beck Depression Inventory (BDI), and evaluation of the 20-m walking time and the steps to
walk 20-m, as well as postural instability.
Acupuncture and BVA treatments will then be performed on the study group, and sham
acupuncture and normal saline injections will be performed on the control group twice a week
for 12 weeks. The waiting group does not receive any added treatment during the 12 weeks.
The initial assessment will be repeated after 12 weeks in all groups. In the study and the
control groups, an additional assessment will be repeated after 16 and 20 weeks.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Treatment
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