Dialysis Clinical Trial
Official title:
A Comparative Study of Mild Hypothermic Circulatory Arrest Versus Moderate Hypothermic Circulatory Arrest on Aortic Surgery.
By comparing the clinical outcome of patients underwent different hypothermic circulatory arrest (mild hypothermic versus moderate hypothermic) during aortic arch surgery, this study aims to determine the optimal hypothermic circulatory arrest strategy for aortic surgery.
Hypothermic circulatory arrest (HCA) is the cornerstone of aortic surgery. It provides a
bloodless and still operative field. But the side effect of hypothermia also draws people's
concern. With the development of surgical techniques and cardiopulmonary bypass (CPB)
management, the temperature of HCA has been raised from deep hypothermia (14.1-20 degree) to
moderate hypothermia (20.1-28 degree), and it has been a primary choice for many surgeons
around the world. Some of surgeons still tried to push the limit and started using mild
hypothermia (28.1-34 degree), and satisfactory outcome was obtained. However, the optimal
temperature of HCA has not yet been determined.
In this randomized controlled study, 80 informed and consenting patients who are scheduled
for total arch replacement with concomitant proximal aortic reconstruction will be randomized
to mild (28.1-34 degree) or moderate (20.1-28 degree) hypothermia during circulatory arrest.
Clinical outcomes of both groups will be analyzed to determine the optimal temperature for
HCA.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT05031013 -
Trace Elements Concentration in Dialysis
|
||
| Not yet recruiting |
NCT03090828 -
Economic Evaluation of an Education Platform for Patients With End-stage Renal Disease
|
N/A | |
| Completed |
NCT01685372 -
Immunogenicity of Fluzone High Dose in Immunocompromised Children and Young Adults
|
Phase 2 | |
| Active, not recruiting |
NCT01394770 -
Aliskiren or Amlodipine in Hypertensive Hemodialysed Patients
|
Phase 4 | |
| Completed |
NCT00537979 -
Efficacy and Safety of 6 Months Treatment With Paricalcitol Injection or Oral in Patients With Secondary Hyperparathyroidism on Dialysis
|
Phase 4 | |
| Completed |
NCT00506441 -
A Phase 3, Randomized, Double Blind, Placebo-Controlled, Multi-Center, Withdrawal Study of MCI-196 in CKD on Dialysis With Hyperphosphatemia
|
Phase 3 | |
| Completed |
NCT05415969 -
CKD-aP Among Adults on Dialysis in Switzerland
|
||
| Recruiting |
NCT04024007 -
Determination of Citrate Clearance Used in Regional Anticoagulation of Continuous Venous Hemofiltration Circuits
|
||
| Completed |
NCT03772171 -
Estimate for Dietary Intakes and Hemodialysis Patients
|
||
| Recruiting |
NCT02586402 -
Safety & Efficacy of Pegolsihematide for Treatment of Anemia in Participants on Dialysis
|
Phase 2 | |
| Active, not recruiting |
NCT01693263 -
Outcome of BCF Access in Hemodialysis Patients
|
||
| Completed |
NCT01421771 -
Blood Pressure in Dialysis Patients
|
N/A | |
| Active, not recruiting |
NCT01065389 -
Resistance Training in Intradialysis Patients
|
Phase 2 | |
| Completed |
NCT00544492 -
Study of Pain, Anxiety and Complications Related to Cannulation of Arteriovenous (AV) Fistula in Chronic Hemodialysis Patients
|
Phase 4 | |
| Completed |
NCT03910426 -
Prognostic Determinants of Survival and Quality of Life in Prevalent End-stage Kidney Disease Patients
|
||
| Completed |
NCT04565522 -
Transmission of COVID-19 Virus Among Patients and Staff in Dialysis Centers
|
||
| Completed |
NCT04667741 -
Post-dialysis Recovery Time and Affecting Factors Between Turkey and Portugal
|
||
| Completed |
NCT04655989 -
A Study to Demonstrate the Safety and Effectiveness of the NIKKISO DBB-EXA ES Hemodialysis Delivery System
|
N/A | |
| Completed |
NCT05125848 -
Clinical Evaluation of the CM-1500 During Hemodialysis
|
N/A | |
| Completed |
NCT04633915 -
Antibody Response in Hemodialysis and Non-dialysis Patients Diagnosed With COVID-19.
|