Autologous Cord Blood Cells for Brain Injury in Term Newborns

Status Completed

Clinical Trial Summary

This is a pilot study to test feasibility and safety of collection, preparation and infusion of a baby's own (autologous) umbilical cord blood during the first 3 days of age if the baby is born with signs of brain injury. The cord blood used is fresh (not frozen and then thawed).

Clinical Trial Description

The purpose of this pilot study is to evaluate the safety and feasibility of infusions of autologous (the patient's own) umbilical cord blood cells in term gestation newborn infants with hypoxic-ischemic encephalopathy. For this study, infants who have signs of moderate to severe encephalopathy at birth and have cord blood collected at birth can receive their own cord blood cells during the 3 days of age. Babies will be followed for neurodevelopmental outcome at 1, 4 - 6, 9 - 12 months and 18-24 months. MRI brain will be obtained at 1-2 weeks and 4-6 months old. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01649648
Study type	Interventional
Source	National University Hospital, Singapore
Contact
Status	Completed
Phase	Phase 1
Start date	September 2011
Completion date	November 2015

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See also
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