Hypoxia Clinical Trial
Official title:
Aspects of Neuropsychological Assessment, Standard and Sleep Efficiency in People Exposed to Altitude
Aim: To evaluate the influence of oxygen deficit on the cognitive performance and also about
the architecture and sleep efficiency in volunteers subjected to mild and moderate exercise
in a hypobaric chamber. SUMMARY: Participants in this study 30 healthy male volunteers, aged
20 to 40 years, regular physical activity, constituting three groups: 1 - without
exercise-hypoxia group 10 volunteers who not be subjected to any kind of physical exercise
in hypoxia and remain all day of experiment, 2 - group exercise at sea level, is composed of
10 volunteers who will undergo a protocol exercise physical sea-level, 3 - group exercise
and hypoxia - 10 volunteers who will carry out a protocol exercise on a treadmill, being the
same in condition of hypoxia (hypobaric chamber). All groups on the first day of the
experiment will undergo baseline assessments, laboratory blood analysis salivary and
spirometric testing. Assessments will be personality and neuropsychological. After baseline
assessments, the last day of the experiment, the groups will be evaluated again 4350m above
sea level the sea, by personality tests, neuropsychological and laboratory. RATIONALE AND
BACKGROUND: During exposure to environments with a partial reduction of oxygen, human body
can undergo several physiological and psychological changes are not prepared for such
condition. Few studies have reported that the elevation changes and cognitive aspects
related to sleep.
MATERIAL AND METHOD: They describe the procedures to be performed, and the study conducted
in local with adequate infrastructure.
ADDITIONAL RISKS TO THE PATIENT: Minimal risk, mild discomfort, involving blood collect.
Purpose: To evaluate the influence of oxygen deficit on the cognitive performance and also
about the architecture and sleep efficiency in volunteers subjected to mild and moderate
exercise in a hypobaric chamber.
SUMMARY: Participants in this study 30 healthy male volunteers, aged 20 to 40 years, regular
physical activity, constituting three groups: 1 - without exercise-hypoxia group 10
volunteers who not be subjected to any kind of physical exercise in hypoxia and remain all
day of experiment, 2 - group exercise at sea level, is composed of 10 volunteers who will
undergo a protocol exercise physical sea-level, 3 - group exercise and hypoxia - 10
volunteers who will carry out a protocol exercise on a treadmill, being the same in
condition of hypoxia (hypobaric chamber). All groups on the first day of the experiment will
undergo baseline assessments, laboratory blood analysis salivary and spirometric testing.
Assessments will be personality and neuropsychological. After baseline assessments, the last
day of the experiment, the groups will be evaluated again 4350m above sea level the sea, by
personality tests, neuropsychological and laboratory. RATIONALE AND BACKGROUND: During
exposure to environments with a partial reduction of oxygen, human body can undergo several
physiological and psychological changes are not prepared for such condition. Few studies
have reported that the elevation changes and cognitive aspects related to sleep
;
N/A
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04498598 -
Structural Modification In Supraglottic Airway Device
|
N/A | |
| Completed |
NCT05532670 -
N600X Low Saturation Accuracy Validation
|
||
| Enrolling by invitation |
NCT04106401 -
Intravascular Volumes in Hypoxia During Antarctic Confinement
|
N/A | |
| Recruiting |
NCT05883137 -
High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill
|
||
| Not yet recruiting |
NCT05817448 -
Hypoxia-induced Autophagy in the Pathogenesis of MAP
|
||
| Recruiting |
NCT02661152 -
DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy of HNSCC.
|
Phase 3 | |
| Terminated |
NCT02801162 -
Evaluation of Accuracy and Precision of a New Arterial Blood Gas Analysis System Blood in Comparison With the Reference Standard
|
N/A | |
| Completed |
NCT02943863 -
Regional Ventilation During High Flow Nasal Cannula and Conventional Nasal Cannula in Patients With Hypoxia
|
N/A | |
| Not yet recruiting |
NCT02201875 -
Intrinsic Periodic Pattern of Breathing
|
N/A | |
| Completed |
NCT02105298 -
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
|
N/A | |
| Completed |
NCT01922401 -
Inverse Ratio Ventilation on Bariatric Operation
|
N/A | |
| Active, not recruiting |
NCT01681238 -
Goal-directed Therapy in High-risk Surgery
|
N/A | |
| Completed |
NCT01463527 -
Using Capnography to Reduce Hypoxia During Pediatric Sedation
|
N/A | |
| Completed |
NCT01507623 -
Value of Capnography During Nurse Administered Propofol Sedation (NAPS)
|
N/A | |
| Withdrawn |
NCT00638040 -
The Gene Expression Studies of the Role of Tumor Microenvironments in Tumor Progression
|
N/A | |
| Active, not recruiting |
NCT06097754 -
Intermittent Exogenous Ketosis (IEK) at High Altitude
|
N/A | |
| Completed |
NCT04589923 -
The VISION-Acute Study
|
||
| Completed |
NCT05044585 -
Evaluation of RDS MultiSense® in Desaturation Analysis in Healthy Volunteers
|
N/A | |
| Completed |
NCT03659513 -
The Effect of ECMO on the Pharmacokinetics of the Drugs and Their Clinical Efficacy
|
||
| Completed |
NCT03221387 -
Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients
|
N/A |