The Effects of Vibration on Hypoxia

Hypoxia Clinical Trial

Official title:

The Effects of Vibration on Hypoxia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01245491
• Other study ID #: REK-2010/2021b
• Status: Completed
• Phase: N/A
• First received: November 19, 2010
• Last updated: January 13, 2011
• Start date: October 2010
• Est. completion date: December 2010

Study information

• Verified date: January 2011
• Source: Institute of Aviation Medicine, Oslo, Norway
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway: Regional Ethics Commitee
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is:

1. To study the effect of whole-body vibration on partial pressure of oxygen in arterial blood (PaO2), under hypobaric hypoxic conditions.

2. To study the effects of whole-body vibration and hypobaric hypoxia on visual contrast sensitivity.

3. To se if there is an increase in cytokines and other biomarkers under different hypobaric hypoxic conditions Our main hypothesis is that whole-body vibration may cause PaO2 to drop to a lower level, at a given altitude; than would be the case if there were no vibration present.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 13
• Est. completion date: December 2010
• Est. primary completion date: December 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

Exclusion Criteria:

• Stay at altitude over 2000 m last two weeks prior to study-start.

• Severe head injury

• Cardiovascular disease

• lung disease

• Decompression sickness

Study Design

Intervention Model: Crossover Assignment, Masking: Single Blind (Subject), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Hypoxia

Intervention

Other:
• Vibration
Whole-body vibration, 17 Hz, 1.1ms-2

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Institute of Aviation Medicine, Oslo, Norway

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	PaO2	Assessed at six different altitudes	14 minutes	Yes
Primary	PaO2	Assessed at six dfferent altitudes	35 minutes	Yes
Secondary	Ventilation	Assessed at six different altitudes, over a period of three minutes.	14 minutes	No
Secondary	Ventilation	Assessed over a periode of three minutes, at six different altitudes.	35 minutes	No