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Hypoxemia clinical trials

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NCT ID: NCT03311087 Recruiting - Hypoxemia Clinical Trials

Conduct of Nasal High Flow Oxygen in Acute Respiratory Failure

DECIPHEROBS
Start date: July 9, 2018
Phase:
Study type: Observational

Although many studies have investigated the clinical benefits of nasal high flow during acute hypoxemic respiratory failure, there is no data (and even less so recommendations) on how to best conduct this technique, including its initiation and its weaning periods. Investigators will assess in a multicenter, observational study, the way clinicians use nasal high flow therapy in patients with acute respiratory failure in order to try identify one or more strategies that may be then compared in an interventional study.

NCT ID: NCT03009643 Recruiting - Hypoxemia Clinical Trials

Salvage Treatment of Inhaled Nitric Oxide in Patients With Refractory Hypoxemia After Aortic Surgery

Start date: October 2016
Phase: N/A
Study type: Interventional

Hypoxemia is a common complication after aortic surgery. As this complication has an adverse effect on the postoperative course of the patient, early treatment is important; however, the mechanism of hypoxemia after surgery for acute aortic dissection remains unclear. Recently, the investigators found that inhaled Nitric Oxide can improve the oxygenation in some of these patients. The investigators are trying to evaluate the effectiveness and safety of inhaled Nitric Oxide in patients with refractory hypoxemia after aortic surgery.

NCT ID: NCT02713737 Recruiting - Hypoxemia Clinical Trials

The Correlation Between Sleep Quality and Atrial Fibrillation Undergoing High-flow Nasal Cannula Oxygen (HFNC)

Start date: April 2016
Phase: Phase 4
Study type: Interventional

The investigators hypothesized that heated humidified high-flow nasal cannula oxygen(HFNC) along with high quality of sleep, in comparison with noninvasive positive pressure ventilation (NIV), could reduce the release of inflammatory marker C-reactive protein(CRP), which as independent predictor of atrial fibrillation(AF), further lower the incidence of new-onset AF following coronary artery bypass grafting(CABG).

NCT ID: NCT02589691 Recruiting - Hypoxemia Clinical Trials

Neuromuscular-Blocking Agents and Hypoxemia During Intubation in Infants (ROC-HYPOX)

ROC-HYPOX
Start date: December 23, 2015
Phase: Phase 4
Study type: Interventional

The prevention of the occurrence of respiratory events is a constant concern in pediatric anesthesia, as these represent the main cause of the anesthesic mortality. These events occur partly during induction of anesthesia and are all the more frequent as the child is young. The French recommendations do not propose the use of neuromuscular-blocking agents in pediatric anesthesia. This recommendation is controversial In a recently published study, it has been shown that the use of neuromuscular blocking agents during induction in children under 2 years improves intubating conditions and reduces the incidence of hemodynamic and respiratory events. This monocentric study, centered on intubating conditions, does not allow to conclude on the influence of muscle relaxants on reduction of the respiratory morbidity. The objective of study is to demonstrate that, in children under 2 years, changing the anesthesia protocol can reduce the incidence and severity of episodes of hypoxemia associated with respiratory events occurring during induction

NCT ID: NCT02287220 Recruiting - Hypoxia Clinical Trials

Non Contact Measurement of Vital Signs

Start date: November 2014
Phase:
Study type: Observational

The purpose of this study is to test the accuracy of a web cam-based biomedical device developed at UVA (not FDA-approved) that is designed to measure heart rate, respiratory rate, and oxygen saturation without requiring any patient contact. One potential application of such a device would be in the field of infant monitoring allowing parents (and physicians) to monitor the vital signs of infants continuously. The investigators therefore propose to record the heart rate, respiratory rate, and oxygen saturation of 100 infants (defined as children aged 12 months or less) who are receiving continuous oxygen, heart rate, and respiratory rate monitoring with a traditional vital signs monitor. The relationship between "non-contact" and "gold standard" (GE monitoring equipment) heart rate, respiratory rate, and oxygen saturation will be analyzed using regression and limits of agreement analysis.

NCT ID: NCT01595399 Recruiting - Bradycardia Clinical Trials

Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation

Start date: April 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare heart rate in infants who receive atropine as a part of their medication before intubation to those who do not. To be able to find out , we need to divided babies into 2 groups; group 1 : receives atropine + sedation + muscle relaxant group 2 : receives water or saline ( placebo group) + sedation + muscle relaxant Then we need to compare heart rate during intubation and duration of intubation between the 2 groups.

NCT ID: NCT01370993 Recruiting - Clinical trials for Obstructive Sleep Apnea

The Prediction Model of Hypoxemia for Safe Bronchoscopy

Start date: May 2011
Phase: N/A
Study type: Observational

The purpose of this study is to develop the hypoxemia prediction model during fiberoptic bronchoscopy under MAC(monitored anesthesia care) anesthesia.

NCT ID: NCT00510770 Recruiting - Hypoxemia Clinical Trials

CPAP in Liver Transplant

Start date: December 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine the effectiveness of continuous positive airway pressure compared to standard treatment in preventing the need for intubation and mechanical ventilation in patients who develop acute hypoxemia after liver transplant. Hypoxemia complicates the recovery of 30-50 % of patients after abdominal surgery; endotracheal intubation and mechanical ventilation may be required in 8-10 % of cases increasing morbidity and mortality and prolonging intensive care unit and hospital stay.