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Hypoxemia clinical trials

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NCT ID: NCT01620307 Completed - Hypoxemia Clinical Trials

Rapamune Improves Outcomes of Severe H1N1 Pneumonia

Start date: June 2009
Phase: Phase 2
Study type: Interventional

Severe H1N1 pneumonia with acute respiratory failure shows hyperactive immune cells infiltration of lung. Rapamune, a mTOR inhibitor, modulates the immune response by blocking activation of T- and B-cells. To investigate the clinical efficiency of rapamune in severe H1N1 pneumonia with respiratory failure, this study was conducted.

NCT ID: NCT01595399 Recruiting - Bradycardia Clinical Trials

Atropine Versus no Atropine for Neonatal Rapid Sequence Intubation

Start date: April 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare heart rate in infants who receive atropine as a part of their medication before intubation to those who do not. To be able to find out , we need to divided babies into 2 groups; group 1 : receives atropine + sedation + muscle relaxant group 2 : receives water or saline ( placebo group) + sedation + muscle relaxant Then we need to compare heart rate during intubation and duration of intubation between the 2 groups.

NCT ID: NCT01587157 Completed - Hypoxemia Clinical Trials

Capnography During Percutaneous Transhepatic Cholangiodrainage (PTCD) (HepaBreath)

Start date: August 2010
Phase: Phase 3
Study type: Interventional

Capnography provides noninvasive monitoring of ventilation and can allow early recognition of altered respiration patterns and apnea. The aim of this prospective study was to compare the detection of apnea and the prediction of oxygen desaturation and hypoxemia by capnography versus clinical surveillance during procedural sedation for percutaneous transhepatic cholangiodrainage (PTCD).

NCT ID: NCT01477450 Completed - Hypoxemia Clinical Trials

Comparison of Oxygen Delivery Devices for Reversal of Altitude-Induced Hypoxemia in Normal Subjects

Start date: October 2011
Phase: N/A
Study type: Interventional

This study will compare the ability of pulsed-dose oxygen from a concentrator to reverse altitude-induced hypoxemia compared to compressed gas from a standard oxygen cylinder.

NCT ID: NCT01470170 Completed - Hypoxemia Clinical Trials

Regimen of Alfentanil in Propofol Sedative Fibro-bronchoscopy

Start date: October 2010
Phase: Phase 4
Study type: Interventional

Alfentanil (Alf) is used in combination with Propofol (Pro) in fiber-bronchoscopy and in many other conscious sedation procedures. Alf and Pro have the characteristic of rapid anesthetic onset and quick recovery, synergic sedative effect and unwanted side effects too. However, the amount of Alf needed in combination with Pro for induction and the timing of administration was no standardized. The investigators designed this study to evaluate the optimal regimen, dose and timing of Alf in Target-Controlled infusion (TCI) of Pro for flexible bronchoscopy sedation, and also to evaluate the influence of variable regimen of Alf and Pro on hypoxemia, hypotension, cough severity, and Pro injection related pain.

NCT ID: NCT01457651 Completed - Hypoxemia Clinical Trials

Comparison of Four Different Recruitment Maneuvers in Patients After Coronary Surgery

RECR-CABG
Start date: March 2010
Phase: N/A
Study type: Interventional

The risk of respiratory failure after cardiac surgery is high, and it may result in many complications. The maneuver of alveolar recruitment may improve the oxygen transport in the human organism. The investigators compare three different types of alveolar recruitment in patient after cardiac surgery, to reveal which one is better.

NCT ID: NCT01377051 Completed - COPD Clinical Trials

Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea

Start date: May 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether indacaterol maleate 300 micrograms (mcg) is effective in the acute treatment of COPD and in particular on reducing lung hyperinflation and dynamic volumes.

NCT ID: NCT01370993 Recruiting - Clinical trials for Obstructive Sleep Apnea

The Prediction Model of Hypoxemia for Safe Bronchoscopy

Start date: May 2011
Phase: N/A
Study type: Observational

The purpose of this study is to develop the hypoxemia prediction model during fiberoptic bronchoscopy under MAC(monitored anesthesia care) anesthesia.

NCT ID: NCT01085539 Completed - Hypoxemia Clinical Trials

Oxygen Saturation Alarms in the Neonatal Intensive Care Unit

Start date: January 2010
Phase: N/A
Study type: Observational

Infants will be observed in the neonatal intensive care unit for 4 hours. The observer will note the timing of oxygen saturation alarms, staff response, and interrupted staff activities.

NCT ID: NCT01072487 Completed - Hypoxemia Clinical Trials

Capnography During Colonoscopy

ColoCap
Start date: February 2010
Phase: Phase 3
Study type: Interventional

In the study the value of capnography for avoiding complications during sedation for colonoscopy is evaluated.