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Hypovolemia clinical trials

View clinical trials related to Hypovolemia.

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NCT ID: NCT04733547 Completed - Hypovolemia Clinical Trials

Spectral Analysis of Central Venous Pressure Waveform

Start date: February 22, 2021
Phase:
Study type: Observational

The use of central venous pressure has been abandoned for the assessment of intravascular volume status. The dynamic fluctuation of central venous pressure according to heart rate is quantitatively measured by spectral analysis of the central venous pressure waveform. Its clinical utility in the assessment of intravascular volume status is investigated.

NCT ID: NCT04641949 Completed - Analgesia Clinical Trials

Methoxyflurane and Fentanyl in LBNP

Start date: November 18, 2020
Phase: Phase 4
Study type: Interventional

The study is a single-centre, placebo-controlled, crossover study on healthy volunteers aiming to explore non-inferiority of methoxyflurane and fentanyl compared to placebo on the tolerance to hypovolemia.

NCT ID: NCT04573842 Completed - Hypovolemia Clinical Trials

Ultrasound Assessment of the Subclavian Vein for Predicting Hypotension in Children After Anaesthesia Induction

Start date: November 30, 2020
Phase:
Study type: Observational

Intra operative hypotension is a risk factor in pediatric anesthesia (McCann ME et al.Pediatr Anesth 2014; 24: 68-73). In summary, the study aims at examine if ultrasound assessment of the diameter and collapsibility index of the subclavian vein is correlated to fasting time and if they are correlated to the degree of hypotension seen post anesthesia induction in children undergoing general anesthesia.

NCT ID: NCT04402190 Completed - Hyponatremia Clinical Trials

Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status

Start date: June 1, 2018
Phase:
Study type: Observational

Hyponatremia is the most frequent electrolyte disorder encountered in clinical practice. The patient approach, however, is still problematic, above all because hyponatremia is a manifestation correlated to various pathological conditions, with complex etiopathogenesis. Even though some algorithms have been proposed to correctly assess hyponatremia subtype classification and patient volume status, there is no single parameter that has proven to be able alone to perfectly achieve this result.

NCT ID: NCT04388722 Withdrawn - Hypovolemia Clinical Trials

Monitoring Noninvasively for Infusion and Transfusion Optimization

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

This is a multicenter, cluster randomized controlled trial to assess the effects of an optimized intraoperative fluid and blood management strategy on postoperative complications.

NCT ID: NCT04298931 Completed - Fluid Overload Clinical Trials

Prediction of the Effect of Fluid Administration Using Arterial Pressure and Ventilator Data During Abdominal Surgery

Start date: May 15, 2020
Phase:
Study type: Observational

It is well known, that patients with circulatory impairment sometimes, but not always, benefit from intravenous fluids. Predicting if a fluid administration will improve circulation is therefore of substantial clinical interest. Ventilator treatment induces cyclic variation in blood pressure due to interaction between the lungs and the heart. This variation is minor, but its amplitude may be used for guiding fluid administration. However, this method of using ventilator-induced variation in blood pressure to predict the effect of fluid administration was developed when different settings for ventilator treatment was recommended, compared with today. With today's recommend ventilator treatment, the method is, unfortunately, less reliable. The investigators will investigate how different ventilator settings influence variation in blood pressure, and the investigators will test if this knowledge allows us to better predict the effect of a fluid administration, by taking the ventilator settings into account.

NCT ID: NCT04283851 Completed - Surgery Clinical Trials

Dynamic Parameters in Evaluation of Fluid Responsiveness

Start date: February 1, 2020
Phase:
Study type: Observational

Intravenous infusion of fluids in patients after surgery is a very important part of treatment. However, administering too much or too little fluid can lengthen the stay in the intensive care unit or even harm the patient. Therefore, fluid therapy should be tailored to the individual needs of each patient. Several methods are available to assess which patients will likely benefit from fluid administration. However, each of these methods is useful only under certain conditions. The study aims to explore some less-known, yet promising tests which could make adequate fluid administration more precise and easier to achieve.

NCT ID: NCT04257136 Active, not recruiting - Sepsis Clinical Trials

VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients

Start date: February 17, 2020
Phase: Phase 2
Study type: Interventional

This study is being conducted to evaluate the safety and effectiveness of VBI-S in elevating the blood pressure of septic shock patients with absolute or relative hypovolemia.

NCT ID: NCT04202432 Completed - Hypovolemia Clinical Trials

Clinical Validation of Algorithms for Mean Systemic Filling Pressure and Automated Cardiac Output

PP3D
Start date: June 24, 2019
Phase:
Study type: Observational

Prospective combined clinical validation of an algorithmic calculated mean systemic filling pressure (Pms-Nav) with the gold standard for Pms (Pms calculated from venous return curves during inspiratory hold procedures with incremental airway pressures; Pms-Insp). Secondary correlation between invasive cardiac output measurement versus 3D TOE and carotid echo doppler measured cardiac output.

NCT ID: NCT04186416 Recruiting - Hemorrhage Clinical Trials

Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients

MOSTCARE-PED
Start date: May 3, 2023
Phase:
Study type: Observational

The Pressure Recording Analytical Method, invasive hemodynamic monitoring, is an uncalibrated pulse contour analysis, installed in the Mostcare® system that allows a continuous estimation of the stroke volume and thus the cardiac output, by the relationship between the area under the curve of the systolic portion of the arterial blood pressure curve and the dynamic impedance of the cardiovascular system. The objectives of the study are to determine if the parameters measured by Mostcare® make it possible to predict the response to volume expansion in pediatric surgical critical care patients, sedated, intubated and ventilated, by comparing the changes in stroke volume, induced by a volume expansion, measured by trans-thoracic echocardiography.