Arimidex Multicenter Trial in Growth Hormone (GH) Deficient Boys

Status Completed

Clinical Trial Summary

The purpose of this study is to see if Arimidex, an aromatase inhibitor, can delay epiphyseal fusion and increase predicted adult height in boys who are growth hormone deficient, in puberty, and who are taking growth hormone. This is a double blind, placebo controlled 3 year trial.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)

Related Conditions & MeSH terms

Hypopituitarism

Clinical Trial Details

NCT number	NCT00133354
Study type	Interventional
Source	Nemours Children's Clinic
Contact
Status	Completed
Phase	Phase 2/Phase 3
Start date	November 2001
Completion date	August 2010

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT02871986` - Pubertal Induction in Individuals With Hypogonadism	N/A
Completed	`NCT00851942` - Determination of Method-specific Normal Cortisol and Adrenal Hormone Responses to the Short Synacthen Test	Phase 4
Completed	`NCT00507104` - Pituitary Functions After Traumatic Brain Injury (TBI) and/or Subarachnoid Hemorrhage (SAH)
Completed	`NCT01088399` - A Prospective Observational Study of Effect of Somatropin on Growth Hormone Deficient Adults	N/A
Completed	`NCT00027430` - Androgen Replacement Therapy in Women With Hypopituitarism	N/A
Recruiting	`NCT04897802` - Identification and Clinical Relevance of an Oxytocin Deficient State (GLP1 Study)	Phase 4
Not yet recruiting	`NCT06014398` - Improving Survivorship and Health-related Quality of Life in Patients With Primary Brain Tumours	N/A
Recruiting	`NCT04121780` - Growth Hormone Replacement Therapy for Retried Professional Football Players	Phase 2
Not yet recruiting	`NCT01666964` - Hormone Deficiency After Brain Injury During Combat	N/A
Completed	`NCT01028742` - Posttraumatic Hypopituitarism - Incidence, Predictors and Test Validity	N/A
Completed	`NCT00139945` - Ghrelin, Growth Hormone and Cortisol Interaction in Growth Hormone Deficient Patients	N/A
Completed	`NCT05206149` - Stimulation Test With Intranasal Glucagon for Corticotroph, Somatotroph and Antidiuretic Axes	Phase 4
Completed	`NCT05188131` - Acute Neuroendocrine Response to Intravenous Infusion of Diclofenac Sodium	Phase 4
Not yet recruiting	`NCT03708523` - Next Day Growth Hormone Predicting Pituitary Function After Adenomectomy
Completed	`NCT01007071` - Effects of Growth Hormone on Cognition and Cerebral Metabolism in Adults With Growth Hormone Deficiency	Phase 3
Completed	`NCT00080483` - Testosterone and Growth Hormone for Bone Loss in Men	Phase 2
Completed	`NCT01009905` - An Observational Study (Registry) Assessing Treatment Outcomes and Safety for Children and Adults Who Are Prescribed Norditropin® (Human Growth Hormone)	N/A
Completed	`NCT01209416` - The Effect of Pharmacological Antilipolysis on the Metabolic Effects of Ghrelin	N/A
Completed	`NCT04902235` - Identification and Clinical Relevance of an Oxytocin Deficient State (CRH Study)	Phase 4
Not yet recruiting	`NCT06326853` - Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models