The Effect of Testosterone Replacement on Endothelial Dysfunction,

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Clinical Trial Summary

The study searched for answers to two questions

1. What is the effect of testosterone replacement therapy on endothelial dysfunction, inflammation and insulin resistance?

2. Regarding the above parameters, is there any difference between daily transdermal testosterone implementation and intramuscular injection performed in three weeks.

NCT number	NCT01533129
Study type	Interventional
Source	Gulhane School of Medicine
Contact
Status	Completed
Phase	Phase 4
Start date	August 2008

Status	Clinical Trial	Phase
Not yet recruiting	`NCT02871986` - Pubertal Induction in Individuals With Hypogonadism	N/A
Completed	`NCT02171390` - Endothelial Dysfunction, Inflammation and Insulin Resistance in Congenital Hypogonadism and Effect of Testosteron Replacement Therapy	Phase 4
Completed	`NCT00138710` - Short-term Effects of Aromatase Inhibition in Obese Men	Phase 3

The Effect of Testosterone Replacement on Endothelial Dysfunction, Inflammation and Insulin Resistance in Male Hypogonadotrophic Hypogonadism

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms