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Hypogonadism clinical trials

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NCT ID: NCT02222558 Completed - Hypogonadism Clinical Trials

Oral Testosterone for the Treatment of Hypogonadism in Males

Start date: September 2014
Phase: Phase 2
Study type: Interventional

Low testosterone is a condition that occurs when the body is unable to produce sufficient quantities of testosterone. The medical name for low testosterone is hypogonadism. Hypogonadism can be caused by many factors. Symptoms include: decrease in libido, lack of energy and mood swings. The goal of testosterone replacement therapy is to return testosterone levels to the normal range and relieve symptoms.

NCT ID: NCT02171390 Completed - Clinical trials for Hypogonadotrophic Hypogonadism

Endothelial Dysfunction, Inflammation and Insulin Resistance in Congenital Hypogonadism and Effect of Testosteron Replacement Therapy

Start date: August 2008
Phase: Phase 4
Study type: Interventional

The study searched for answers to two questions 1. Is there endothelial dysfunction, inflammation and insulin resistance in patients with congenital hypogonadotropic hypogonadism? 2. What is the effect of testosterone replacement therapy on endothelial dysfunction, inflammation and insulin resistance?

NCT ID: NCT02159469 Completed - Hypogonadism Clinical Trials

Subcutaneous Testosterone Replacement Efficacy and Safety in Adult Men Diagnosed With Hypogonadism

STEADY
Start date: July 2014
Phase: Phase 3
Study type: Interventional

Evaluation of efficacy and safety of testosterone enanthate administered subcutaneously using an auto-injector

NCT ID: NCT02154477 Completed - Clinical trials for Hypogonadotropic Hypogonadism

Effect of Intranasal Insulin on LH Concentrations in Man

Start date: December 2014
Phase: Phase 1/Phase 2
Study type: Interventional

Over the last few years, studies have shown that men with type 2 diabetes sometimes develop a condition called hypogonadotrophic hypogonadism (HH). People with this condition produce little or no sex hormones. Obesity and metabolic syndrome are also associated with HH. Research suggests that insulin in the brain may benefit the glands that release these hormones. During this study, subjects will spray a small amount of insulin into their nose.This will increase insulin concentrations in the brain. The purpose of this study is to find out the effect of one dose of intranasal insulin on release of LH (a sex hormone) in obese diabetic men with HH.

NCT ID: NCT02149264 Completed - Clinical trials for Adult Male Hypogonadism

A Clinical Trial to Evaluate the Efficacy and Safety of Testosterone Gel in Adult Hypogonadal Males

Start date: July 2014
Phase: Phase 3
Study type: Interventional

This is a phase 3, open-label, non-randomized, clinical trial to evaluate the efficacy and safety of FE 999303 (Testosterone gel) in adult hypogonadal males.

NCT ID: NCT02147964 Withdrawn - Clinical trials for Gonadotropin Deficiency

ITT-5 Mechanisms of Spermatogenesis in Man

ITT-5
Start date: June 2019
Phase: Phase 2
Study type: Interventional

The purpose of this investigational drug study is to determine how much male hormone, testosterone, is needed to maintain sperm production in the testis.

NCT ID: NCT02140515 Recruiting - Infertility Clinical Trials

Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism

Start date: November 2012
Phase: Phase 4
Study type: Interventional

We wanted to compare the Assisted Reproductive Technology (ART) outcomes between two protocols of induction of ovulation in patients with Hypogonadotropic Hypogonadism. In the beginning, all patients receive Recombinant Follicle Stimulating Hormone (Gonal-F) and Recombinant Luteinizing Hormone (Luveris). When at least one follicle reaches 14 mm in diameter, Luveris alone is administered for group A and both drugs Gonal-F and Luveris for group B. Finally Assisted Reproductive Technology (ART) results are compared between the two groups.

NCT ID: NCT02137265 Withdrawn - Hypogonadism Clinical Trials

Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism

Start date: September 2015
Phase: N/A
Study type: Interventional

Hypothesis: Prescribed clomiphene citrate to azoospermic patients with hypoandrogenism could improve the sperm retrieval in either fresh sperm or after surgical sperm extraction.

NCT ID: NCT02111473 Completed - Hypogonadism Clinical Trials

The Effect of Testosteron Replacement Treatment on the Fibroblast Growth Factor-23, Asymmetric Dimethylarginine and Vitamin D Levels in the Congenital Hypogonadotropic Hypogonadism

Start date: May 2009
Phase: Phase 4
Study type: Interventional

The study is designed to answer the following questions: 1) What is the effect of testosteron replacement treatment on the endothelial dysfunction. 2/ What is the effect of testosteron replacement on the bone mineral metabolism.

NCT ID: NCT02111434 Completed - Hypogonadism Clinical Trials

Visceral Adiposity Index and Triglyceride/High-density Lipoprotein Cholesterol Ratio in the Congenital Hypogonadotropic Hypogonadism and Effect of Testosteron Treatment

Start date: July 2013
Phase: Phase 4
Study type: Interventional

The study is designed to answer the following questions: 1. What is the levels of visceral adiposity index and Triglycerides/HDL cholesterol ratio in hypogonadism? 2. What is the effect of testosterone replacement on the visceral adiposity index and Triglycerides/HDL cholesterol ratio?