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Hypertrophic clinical trials

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NCT ID: NCT05126017 Not yet recruiting - Burns Clinical Trials

Examine the Validity of a Panel of Objective Burn Scar Measurement Tools

BOSS-2
Start date: January 2022
Phase:
Study type: Observational

Reliable scar assessment is essential not only when designing clinical trials to investigate the efficacy of new and existing scar therapies, but also in everyday, clinical practice, to examine the progress of our patients' care. Subjective assessments are extremely important; they demonstrate to the patient the changes and improvements in their scars since the primary burn injury. Nevertheless, clinicians require reliable, validated, and objective tools which can yield measurable and reproducible outcomes. These are ultimately needed to achieve the goal of reducing the physical and psychosocial burden of scarring through compelling research. Previously, a pilot study (BOSS-1) was conducted in 55 patients with post burn hypertrophic scars. The investigators measured, among other parameters, scar thickness, density, and pliability, using a panel of objective scar assessment tools, alongside standard subjective measurements (questionnaire-based), and skin biopsy assessments. Measurements were performed at a single time point which varied from 3 months to 6 years post burn injury. This work indicated that measuring scar thickness, pliability and colour together, may provide a global scar objective score. BOSS-2 is a multi-centre study that will validate the preliminary findings in BOSS-1.

NCT ID: NCT03479580 Recruiting - Ischemic Clinical Trials

Coronary Artery Disease and Coronary Microvascular Disease in Cardiomyopathies Registry

3CRegistry
Start date: February 8, 2018
Phase:
Study type: Observational [Patient Registry]

Long-term prognostic value of macrovascular and microvascular coronary artery stenoses in each type of cardiomyopathy.

NCT ID: NCT02692508 Recruiting - Cardiomyopathy Clinical Trials

Prognosis of Subjects With Unexplainable Precordial Deep T-wave Inversion Without Wall Thickness> 15mm

Start date: January 2011
Phase: N/A
Study type: Observational

The investigators sought to evaluate the morphological and functional changes and prognosis of participants with unexplainable precordial deep T-wave inversion on ECG and with apical thickness less than 15mm. The conduction of this study was largely due to the increased clinical requirement, which reflected the increased awareness among physicians of missed AHCM.

NCT ID: NCT02630303 Completed - Wounds Clinical Trials

High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin

Start date: January 2016
Phase: Phase 1
Study type: Interventional

The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.

NCT ID: NCT02063243 Completed - Keloid Clinical Trials

Intralesional Cryotherapy With a Argon Gas Based Device for the Treatment of Keloid and Hypertrophic Scars

Start date: January 2010
Phase: N/A
Study type: Interventional

This prospective evaluation studies the effectiveness of Intralesional (IL) cryotherapy with a argon gas based device in treating keloids and hypertrophic scars in population consisting of all Fitzpatrick skin type patients

NCT ID: NCT01430130 Completed - Hypertrophic Clinical Trials

Investigation of a Novel Silicone Dressing to Maximize the Outcomes of Scar Revision Procedures (IMPROVE)

IMPROVE
Start date: September 2011
Phase: N/A
Study type: Interventional

Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a simple manner.

NCT ID: NCT01399099 Completed - Hypertrophic Clinical Trials

A Study of a Novel Silicone Dressing to Minimize Scar Formation

REFINE
Start date: June 2011
Phase: N/A
Study type: Interventional

Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a simple manner.