Hyperthyroidism Clinical Trial
Official title:
Comparison of Standardized Update Value Using Single-photo Emission Computed Tomography and Computed Tomography Between Grave's Disease (Hyperthyroidism) Patients and Normal Humans
The purpose of this study is to find out the capacity of standardized uptake value (SUV) using single-photo emission computed tomography and computed tomography (SPECT/CT) in diagnosing Grave's Disease (hyperthyroidism).
Traditionally it is considered that only positron emission tomography(PET) has the ability
to obtain standardized uptake value（SUV）while single-photo emission computed
tomography(SPECT) does not have. Recently with the developing of technology, the ability of
SPECT has been extended.
On the other hand, thyroid imaging by SPECT can only play an auxiliary role in
hyperthyroidism diagnosis mainly since it is regarded as nonquantitative. So the
investigators design this study to search the capacity and accuracy of SUV provided by SPECT
and CT(CT is used for reconstruction algorithm) in diagnosing GD.
This is a multiple-center study containing nine groups in China that use GE Discovery NM/CT,
an advanced equipment. Thus, the data can be more accurate and more available.
And this is a perspective clinical trial, taking about eight months. The investigators plan
to evaluate at least 50 Grave's Disease(GD) patients and 50 normal humans as contrast in
all.
Every GD patient must have been diagnosed and the results of thyroid function tests(such as
TSH,FT3,FT4） must be available. If necessary, the patient's rate of iodine uptake should
also be known before he/she being included in this study. As for normal people, the results
of thyroid function tests should be within the range of normal value.
The data of each participant will be gathered and stored. And the data processing will be
done with the help of GE staff, using the software Q.Metrix to get the value of SUVmean,
SUVmax. Finally T test will be used in comparison of the differences.
;
Observational Model: Case Control, Time Perspective: Cross-Sectional
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05774535 -
Prospective, Observational Study on the Carotid Intima-media Thickness in Patients Undergoing Thyroid Surgery
|
||
| Completed |
NCT02375451 -
Effect of Childhood Radioiodine Therapy on Salivary Function
|
N/A | |
| Recruiting |
NCT00525122 -
Treatment of M.Graves With Radioactive Iodine: Follow-up Study
|
N/A | |
| Completed |
NCT01306916 -
Coexisting Thyroid Disease and Hyperparathyroidism
|
N/A | |
| Completed |
NCT03612908 -
TSHβX1 and D2 THR92ALA in Pregnancy
|
||
| Completed |
NCT03393728 -
Heart Rate Variability and Hyperthyroidism: Evaluation of the Short-term Effects of Propanolol
|
Phase 4 | |
| Completed |
NCT05049551 -
Thyroid Uptake Quantification on a New Generation of Gamma Camera
|
||
| Completed |
NCT02514187 -
A Blinded Study Evaluating the Accuracy and Safety of Cyclotron-produced 99mTc in Adult Patients
|
N/A | |
| Completed |
NCT01727973 -
Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves' Orbitopathy
|
Phase 1/Phase 2 | |
| Completed |
NCT03064542 -
The Role of Thyroid Status in Regulating Brown Adipose Tissue Activity, White Adipose Tissue Partitioning and Resting Energy Expenditure
|
||
| Completed |
NCT03951532 -
Morbidity and Mortality Associated With the Care Journey in Children and Adolescents With Hyperthyroidism
|
||
| Recruiting |
NCT04856488 -
Preoperative Lugol's Solution in Graves' Disease and Toxic Nodular Goiter
|
Phase 3 | |
| Active, not recruiting |
NCT02133040 -
Effects of Hyperthyroidism on Amount and Activity of Brown Adipose Tissue
|
||
| Active, not recruiting |
NCT01105923 -
Study of an Intervention to Improve Problem List Accuracy and Use
|
N/A | |
| Recruiting |
NCT03303053 -
Efficacy and Safety of Cholestyramine and Prednisolone as Adjunctive Therapy in Treatment of Overt Hyperthyroidism
|
Phase 3 | |
| Enrolling by invitation |
NCT06452823 -
Efficacy and Safety of Catheter Ablation of Atrial Fibrillation in Patients With Thyroid Hormone Stabilization
|
||
| Completed |
NCT05385029 -
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
|
||
| Not yet recruiting |
NCT05252884 -
Calcium+Calcitriol Versus PTH for the Prevention of Hypocalcemia in Thyroidectomy. Randomized Clinical Trial
|
N/A | |
| Completed |
NCT02499471 -
Brown Adipose Tissue Activity and Thyroid Hormone
|
N/A | |
| Completed |
NCT04825964 -
Exercise Capacity, Physical Activity Levels in Patients With Hyperthyroid
|