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Hyperthyroidism clinical trials

View clinical trials related to Hyperthyroidism.

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NCT ID: NCT06408909 Completed - Hypothyroidism Clinical Trials

Pharmacist Role in Thyroid Disorders

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

Hypothyroidism (HoT) treatment involves lifelong thyroxine replacement therapy and regular monitoring. The objective of this study was to assess the impact of clinical pharmacist (CP) intervention in managing drug-related problems (DRPs) on outcomes among hypothyroid patients receiving levothyroxine (LT4) therapy.

NCT ID: NCT05512715 Completed - Clinical trials for Hyperthyroidism/Thyrotoxicosis

LIthium as Bridging thErapy Prior to Radioactiveiodine in hyperThYroidism

LIBERTY
Start date: January 10, 2021
Phase: Phase 4
Study type: Interventional

A prospective randomised controlled open label, single centre study. subjects will be randomised into lithium or carbimazole arms in a 1:1 ratio. Lithium arm will receive tab Lithium Carbonate 300mg daily while Carbimazole arm will receive tab Carbimazole 10mg daily for a duration of two months prior to radioactive iodine treatment. Changes in the thyroid hormone levels at 2 months of treatment and at months 1,3 and 6 following radioactive iodine will be evaluated.

NCT ID: NCT05385029 Completed - Hypothyroidism Clinical Trials

Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19

COVID-19
Start date: May 1, 2020
Phase:
Study type: Observational [Patient Registry]

The thyroid gland has been shown to be a common target for COVID 19 virus. Babies born to mothers positive for COVID 19 infections were noticed to have elevated thyroid stimulating hormone ( TSH ) levels on screening. Thyroid function tests were monitored in these babies to determine presence of temporary or permanent thyroid disorders following COVID 19 infections during pregnancy.

NCT ID: NCT05118542 Completed - Graves Disease Clinical Trials

Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis

Start date: January 1, 2019
Phase: Phase 3
Study type: Interventional

During July 2019 to August 2020, a single-blind clinical trial was done to 36 patients with Graves' disease. At the beginning of the study, subjects were accommodated into 2 groups, 17 into PTU groups and 19 into methimazole groups. There were 24 subjects who finished the study, 13 from PTU group and 11 from methimazole group. Blood serum was collected for HOMA-IR, LDL-R, NFĸB, sICAM-1, sVCAM-1 and sE-selectin examination. Meanwhile stiffness and thickness of carotid artery was measured using PWV and cIMT.

NCT ID: NCT05098600 Completed - Clinical trials for Rheumatoid Arthritis

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Start date: October 15, 2021
Phase:
Study type: Observational

The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a dermatology clinic of a metropolitan hospital.

NCT ID: NCT05070091 Completed - COVID-19 Clinical Trials

The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course.

ENDO-COVID19
Start date: January 26, 2021
Phase:
Study type: Observational

The main focus of the study is the assessment of hormonal function in the course of COVID-19 infection with special regard for trends predicting clinical events defined as primary endpoints of the study.

NCT ID: NCT05049551 Completed - Hyperthyroidism Clinical Trials

Thyroid Uptake Quantification on a New Generation of Gamma Camera

QUANTHYC
Start date: October 30, 2019
Phase:
Study type: Observational

The primary objective of this study is to evaluate the potential of a new large field CZT gamma camera to estimate the thyroid uptake (TU) on Single photon emission computed tomography (SPECT) and SPECT/CT images in comparison with standard planar scintigraphy. The secondary objective is to analyze the diagnostic contribution of SPECT/CT imaging.

NCT ID: NCT04932135 Completed - Graves Disease Clinical Trials

Resting Heart Rate Monitoring for Optimized Treatment and Surveillance of Hyperthyroidism

PULSAR
Start date: June 8, 2021
Phase:
Study type: Observational

The investigators want to investigate if a continuous heart rate monitoring with a wrist worn fitnesstracker can be useful in the treatment and surveillance of patients suffering from Graves' disease.The aim of our research project is two-fold: First, to evaluate the use of continuous heart rate monitoring as a potential substitute for hormone measurements during treatment of hyperthyroidism. Second, to use continuous heart rate monitoring as a tool for early detection of relapse after discontinuation of antithyroid drugs.

NCT ID: NCT04922801 Completed - Clinical trials for Neuroendocrine Tumors

Optimising Molecular Radionuclide Therapy

SELFIE
Start date: December 9, 2021
Phase:
Study type: Observational [Patient Registry]

This project will examine the role of the whole body, PET and SPECT imaging before, during and after radionuclide treatment for 177Lu-Dotatate therapy, whole body and SPECT imaging for 131-I for thyroid cancer therapy, and whole-body imaging for 131I for hyperthyroidism therapy. Whole-body and SPECT images will be linked to personal dosimeter readings to determine whether - Current radiation protection advice for patients receiving radionuclide treatment is appropriate. - Radiopharmaceutical retention and/or SUV change in patients undergoing repeated radionuclide treatments. - Data combined from early (quantitative imaging) and late (whole-body dose rate measurements) could support individual treatment planning for patients undergoing repeated cycles of molecular therapy.

NCT ID: NCT04825964 Completed - Hyperthyroidism Clinical Trials

Exercise Capacity, Physical Activity Levels in Patients With Hyperthyroid

Start date: March 19, 2021
Phase:
Study type: Observational

The primary aim of the study is to evaluate physical activity level and functional exercise capacity in patients with hyperthyroid. The secondary aim of the study is assessment of respiratory function, peripheral and respiratory muscle strength, respiratory muscle endurance, fatigue, depression, anxiety, stress, sleep and quality of life in patients with hyperthyroid and compare them with healthy controls.