Hyperparathyroidism Clinical Trial
Official title:
Randall's Plaques: Pathogenesis and Relationship to Nephrolithiasis
Kidney stones are very common. They affect 3-5% of the population in the United States. Many people are hospitalized for the treatment of kidney stones and some may die. Better understanding of what causes kidney stones is useful in both the treatment and prevention of kidney stones. However, exactly what causes kidney stones is unknown. The most common type of kidney stones contains calcium, which sometimes is attached to a part of the kidney important in producing the final urine, called the papilla. The investigators have noticed that persons who form kidney stones seem to have more papilla with stones attached. They propose to study these areas of the papilla, called Randall's plaques (named after their discoverer), in patients undergoing surgery for kidney stones.
In order to attempt to explain the pathogenesis of renal calculi, the investigators videotape and document the location and characteristics of each stone, papillae and calyces. One or more small papillary biopsies are taken for analysis to help determine the point of origin of the kidney stone and histological studies are undertaken to determine tissue differences amongst different types of stone formers. Approximately one month after surgery, metabolic studies are undertaken to further review potential causes of stone formation. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00377312 -
7 Day Continuous Parathyroid Hormone IV Infusion
|
Phase 0 | |
Completed |
NCT00379899 -
ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis
|
Phase 4 | |
Completed |
NCT04040946 -
Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention
|
Phase 3 | |
Recruiting |
NCT03053999 -
Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)
|
||
Withdrawn |
NCT02711059 -
Insulin Resistance in Primary Hyperparathyroidism
|
N/A | |
Completed |
NCT01691781 -
The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study
|
N/A | |
Completed |
NCT00887666 -
Pilot Study: Hypovitaminosis D, Hyperparathyroidism and Hypomagnesemia in Patients With Congestive Heart Failure
|
N/A | |
Completed |
NCT00538720 -
Effects of Vitamin D Replacement in Patients With Primary Hyperparathyroidism (PHPT)
|
Phase 1 | |
Terminated |
NCT03044600 -
Gene Expression in Hyperparathyroidism
|
||
Completed |
NCT03747029 -
Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study
|
||
Completed |
NCT01872429 -
Short- and Long-Term Impact of Subtotal Parathyroidectomy on the Achievement of Bone and Mineral Parameters Recommended by Clinical Practice Guidelines in Dialysis Patients
|
N/A | |
Completed |
NCT00800358 -
Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism
|
N/A | |
Completed |
NCT03968510 -
Swalqol in Primary Hyperparathyroidism
|
||
Completed |
NCT00501215 -
Effect of Parathyroidectomy on Sleep
|
N/A | |
Completed |
NCT02591160 -
Optimal HCTZ Cessation for Diagnosis of Hyperparathyroidism
|
N/A | |
Recruiting |
NCT05299632 -
F-18 PSMA for Localization of Parathyroid Adenoma
|
||
Recruiting |
NCT02986607 -
Corticosteroid Rhythms in Hypoparathyroid Patients
|
Early Phase 1 | |
Completed |
NCT02432599 -
Interest of the F18-choline as a Second Line of the Tracer for Detection of Parathyroid Adenomas
|
Phase 2 | |
Completed |
NCT02524041 -
Association Between Serum Periostin Levels and Cortical Porosity in Patients With Secondary Hyperparathyroidism
|
N/A | |
Recruiting |
NCT05667090 -
Effects of Multiple Mega-dose of Vitamin D3 Supplementation on Ameliorating Moderate to Severe Chronic Pain in Hemodialysis Patients
|
N/A |