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Clinical Trial Summary

Current prevention strategies in patients with recurrence of kidney stones show especially in high-risk patients a diversely and in the long-term not successful outcome in a sustainable number of cases. Recent studies have revealed that Dapagliflozin has the potential to decrease risk and incidence of urolithiasis events especially in patients suffering from Diabetes. The investigators propose that Dapagliflozin has the potential to increase the metabolic situation of hyperoxaluric patients with recurrence of urolithiasis. The investigators therefore test whether Dapagliflozin can decrease the oxalate excretion compared to the current strategy with Hydrochlorothiazide. The study may open up a new way of preventing urolithiasis in patients with high-risk of recurring urolithiasis.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05443932
Study type Interventional
Source Medical University of Vienna
Contact Zeljko Kikic, Assoc.Prof.Priv.Doz.Dr
Phone 0043 (0)1 40400 43910
Email zeljko.kikic@meduniwien.ac.at
Status Not yet recruiting
Phase Phase 4
Start date March 4, 2024
Completion date December 31, 2025

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