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Early Versus Conventional Cessation of Hydrocortisone in Septic Shock — CESSHYDRO  

Septic Shock Clinical Trial

Official title:
Composite Adverse Events Compared Early Versus Conventional Cessation of Hydrocortisone in Patients With Septic Shock: Randomized-controlled Trial

Clinical Trial Summary

Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with. The corticosteroid called hydrocortisone is one of the treatment in refractory septic shock which requires vasopressor to maintain blood pressure. In recovery phase of septic shock and weaning off vasopressor, there is no definite way to taper off hydrocortisone.

Clinical Trial Description

According to secondary outcomes of several studies analyzed in systemic review was shown adverse events from corticosteroid uses including hyperglycemia, hypernatremia, muscle weakness, and superimposed infection. This trials will compare composite adverse events in early versus conventional cessation of hydrocortisone in septic shock. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05818826
Study type Interventional
Source Mahidol University
Contact Surat Tongyoo, Doctor
Phone +24197764
Email surat.ton@mahidol.ac.th
Status Recruiting
Phase Phase 2
Start date July 5, 2023
Completion date May 2025
View Details
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