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Hyperkinesis clinical trials

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NCT ID: NCT02281825 Completed - Depression Clinical Trials

Correlating Real and Virtual World Behavioral Fluctuations in Adolescence

Start date: November 2014
Phase: N/A
Study type: Observational

The present study will explore a new approach to ongoing evaluation and monitoring of fluctuations in personality traits via commercial video games. The aim of this longitudinal study is to examine the influence of everyday life event on video games performance as a function of individual differences in gaming behavioral patterns. focusing on the ongoing performance vacillations of the patient on commercial video games will offer insights in to possibly new generation of real time assessment medium of ongoing behavior.

NCT ID: NCT02276209 Completed - Clinical trials for Adult Attention Deficit Hyperactivity Disorder

Dasotraline Adult ADHD Study

Start date: December 2014
Phase: Phase 3
Study type: Interventional

This is a randomized, double blind, multicenter, parallel group, outpatient study evaluating the efficacy and safety of dasotraline in adults with ADHD.

NCT ID: NCT02259517 Terminated - Clinical trials for Attention Deficit Hyperactivity Disorder

An fMRI Study of Stimulant vs. Non-Stimulant Treatment of ADHD

Start date: September 2014
Phase: N/A
Study type: Interventional

Children with Attention-Deficit/Hyperactivity Disorder (ADHD) are typically treated with two types of medications with differing mechanisms of action: stimulants and non-stimulants. The stimulant Vyvanse (lisdexamfetamine, LDX), and the non-stimulant Intuniv (extended-release guanfacine, GXR), are both FDA approved treatment for ADHD. Clinical trials have shown that both medications are effective in reducing ADHD symptoms, although the neurobiological mechanisms by which Vyvanse and Intuniv produce these effects remain unknown. The aim of this study is to examine the mechanisms by which LDX and GXR reduce symptoms in patients with ADHD. MRI scanning will be used to identify treatment-related changes in brain structure and function.

NCT ID: NCT02257216 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder (ADHD)

Vayarin® Medical Food Study for Adults With Attention Deficit Hyperactivity Disorder (ADHD)

Start date: October 2014
Phase: N/A
Study type: Interventional

The primary study objective is to evaluate the efficacy of Vayarin in ADHD adults.

NCT ID: NCT02255513 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

A Trial Evaluating the Efficacy and Safety of HLD200 in Children With ADHD

CEES
Start date: May 2014
Phase: Phase 3
Study type: Interventional

This study will examine the efficacy and safety of HLD200 in patients age 6-12 years with ADHD using a classroom study design.

NCT ID: NCT02253745 Completed - ADHD Clinical Trials

Safety, Tolerability, PK & Efficacy of V81444 in Volunteers With Attention Deficit/ Hyperactivity Disorder (ADHD)

Start date: July 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this research study is to evaluate the safety, tolerability, effectiveness, and pharmacokinetics (PK) of twice daily oral doses of V81444 in adults with ADHD. Pharmacokinetics (PK) is the study of how a drug is absorbed, distributed, metabolized, and eventually eliminated by the body. Pharmacokinetics is what the body does to the drug. Blood samples will be taken throughout the study for PK analysis.

NCT ID: NCT02251743 Completed - Clinical trials for Attention-Deficit/Hyperactivity Disorder

Double-Blind 2-Site Randomized Clinical Trial of Neurofeedback for ADHD

Start date: September 2014
Phase: N/A
Study type: Interventional

Additional treatments with long-term benefit for attention-deficit/hyperactivity disorder (ADHD) are needed; one of the more promising is neurofeedback (EEG biofeedback), which has several randomized controlled trials showing significant benefit, but which are inconclusive because they were not double-blinded; the benefit could have been nonspecific (placebo response). Because of neurofeedback's labor-intensive cost (1 treatment costing as much as a month's medication), It is important to know how much specific benefit it yields. This 2- site placebo-controlled double-blind randomized clinical trial is the first to test for a specific benefit of neurofeedback with adequate power, the first designed and implemented collaboratively by experts in neurofeedback, ADHD, and clinical trials, the first to rigorously monitor quality not only of treatment, but also of placebo and blinding, and the first to follow up for 2 years to examine enduring effect; the results, whether positive or negative, will provide evidence for clinical practice and public policy regarding ADHD.

NCT ID: NCT02251080 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Attention Deficit/Hyperactivity Disorder Internet Survey Study in a College Student Population

Start date: September 2014
Phase: N/A
Study type: Observational

Attention Deficit/Hyperactivity Disorder (ADHD) is a common condition in young adults. There are many safe oral therapies that require daily use to be effective. Because frequent follow-up visits have been shown to increase adherence to medication, we will determine if adherence to oral therapy for ADHD will improve with an intervention involving weekly internet-based contact without an office visit. The primary aim is to determine the effectiveness of an Internet-based survey in improving adherence to therapy for ADHD. Subjects in this study will be either receive a weekly Internet-based survey assessing the prescribed medication and their ADHD, or to receive standard-of-care therapy in which they will take their medication. The following hypothesis is to be tested: A weekly Internet survey will promote improved adherence to oral ADHD medications.

NCT ID: NCT02249299 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder (ADHD)

Experimental Medicine in ADHD - Cannabinoids

EMA-C
Start date: August 2014
Phase: N/A
Study type: Interventional

Adult patients with ADHD commonly report an improvement in behavioural symptoms when using cannabis with some reporting a preference towards cannabis over their ADHD stimulant medication. The EMA-C study aims to investigate the effects of a cannabis based medication, Sativex Oromucosal Spray on behaviour and cognition in adults with ADHD. This will be carried out by conducting a placebo controlled trial. 30 adults with ADHD will take Sativex or a dummy medication (a placebo) every day for 6 weeks. There is a 50% chance of receiving the Sativex or Placebo. Measures of behaviour and cognition will be taken before and after 6 weeks of treatment. We hypothesise that treatment with Sativex will result in improvements in behaviour and cognition above that of the placebo group.

NCT ID: NCT02248948 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder (ADHD)

Superiority of Omega-3 Versus Placebo on the Improvement of ADHD in Children

ECOMEGA
Start date: September 2014
Phase: N/A
Study type: Interventional

This study aims to evaluate the efficacy of an Omega-3 Fatty Acid Supplement on improving the Attention Deficit Hyperactivity Disorder (ADHD) clinical symptoms.