Metformin Use in Patients Undergoing Total Joint Replacement Surgery

Status Not yet recruiting

Clinical Trial Summary

The goal of this pilot, randomized, single-blind, placebo-controlled trial is to evaluate the feasibility of and provide preliminary information for a multi-center randomized controlled trial that will assess the effects of metformin on blood sugar control in patients after total hip or total knee replacement surgery. The primary objective of this study is to assess the feasibility of conducting a large, randomized trial with regards to timely recruitment, study drug administration, protocol adherence, and overall retention in patients undergoing total joint arthroplasty. Secondarily, the investigators aim to obtain preliminary estimates of group-specific outcome means and variances for primary and secondary outcomes of a larger future trial.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Hyperglycemia

Clinical Trial Details

NCT number	NCT06280274
Study type	Interventional
Source	Oregon Health and Science University
Contact	Aidan Morrell
Phone	5034948211
Email	morrella@ohsu.edu
Status	Not yet recruiting
Phase	Phase 4
Start date	February 26, 2024
Completion date	May 30, 2025

View Details

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