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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03094533
Other study ID # YUMC 2017-02-036
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 3, 2017
Est. completion date November 30, 2018

Study information

Verified date January 2019
Source Yeungnam University College of Medicine
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study was to evaluate the efficacy and safety of sevoflurane-only Volatile induction and maintenance anesthesia (VIMA) and total intravenous anesthesia (TIVA) using only propofol in adult patients scheduled for elective lobectomy surgery. We would like to know if there is a difference in blood glucose levels during surgery and whether the cause is due to the difference in secretion of insulin and cortisol. In addition, we aim to contribute to the improvement of the prognosis of the patients by helping the selection of general anesthesia more effective in maintaining homeostasis in the surgical patients by general anesthesia and further controlling the blood glucose level.


Description:

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Study Design


Related Conditions & MeSH terms


Intervention

Drug:
TIVA
total intravenous anesthesia with propofol
VIMA
volatile induction and maintenance anesthesia with sevoflurane

Locations

Country Name City State
Korea, Republic of Yeungnam University Hospital Daegu

Sponsors (1)

Lead Sponsor Collaborator
Yeungnam University College of Medicine

Country where clinical trial is conducted

Korea, Republic of, 

References & Publications (2)

Cok OY, Ozkose Z, Pasaoglu H, Yardim S. Glucose response during craniotomy: propofol-remifentanil versus isoflurane-remifentanil. Minerva Anestesiol. 2011 Dec;77(12):1141-8. Epub 2011 May 20. — View Citation

Kitamura T, Kawamura G, Ogawa M, Yamada Y. [Comparison of the changes in blood glucose levels during anesthetic management using sevoflurane and propofol]. Masui. 2009 Jan;58(1):81-4. Japanese. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Perioperative glucose level The blood glucose level measured by the patient's blood sample up to 1 hour after surgery
Secondary Perioperative insulin and cortisol levels Insulin and cortisol concentrations measured in blood samples of patient Baseline, 1 hour after incision, intraoperative, 1 hour after surgery
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