Clinical Trials Logo

Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT02335996
Other study ID # 2014-23
Secondary ID 2014-A01302-45RC
Status Completed
Phase N/A
First received
Last updated
Start date December 8, 2014
Est. completion date May 25, 2023

Study information

Verified date May 2023
Source Assistance Publique Hopitaux De Marseille
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Identifying hypercortisolism patients at risk for cardio-vascular events despite biological cure, and determine which patients should be particularly followed. Hypercortisolic patients represent an ideal in vivo model to determine the interactions between glucocorticoids and ectopic fat development.


Read more »

Study Design


Intervention

Biological:
Blood samples for measuring adiponectin, leptin and omentin plasma

Device:
MRI at 3 Tesla
Evaluation by MRI at 3 Tesla of the amount of ectopic fat heart, liver and pancréas and bone marrow.

Locations

Country Name City State
France Assistance Publique Hôpitaux Marseille Marseille

Sponsors (1)

Lead Sponsor Collaborator
Assistance Publique Hopitaux De Marseille

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary measuring the volume of epicardial adipose tissue, as measured by MRI to 3 Tesla. 36 months
Primary Assess insulin resistance by the blood sugar and insulin levels 36 months
Primary Assess cardiovascular risk by a blood complete lipid profile 36 months
Secondary Assess insulin resistance by the blood leptin, adiponectin and omentin plasma level 36 months
Secondary Assess cardiovascular risk by the blood leptin, adiponectin and omentin plasma level 36 months
See also
  Status Clinical Trial Phase
Terminated NCT03379363 - Retrospective Chart Review Study of Pediatric Patients Treated With Korlym for Cushing Syndrome
Recruiting NCT04045015 - Liquorice and Salivary Cortisol N/A
Recruiting NCT06430528 - A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement
Recruiting NCT05772169 - Study to Determine the Prevalence of Hypercortisolism in Patients With Type 2 Diabetes and Treatment With Korlym® (Mifepristone) (CATALYST) Phase 4
Recruiting NCT05368090 - Endoscopic Ultrasound-guided Radiofrequency Ablation in Primary Aldosteronism N/A
Not yet recruiting NCT06246357 - Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism Phase 2
Not yet recruiting NCT04433819 - Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients
Active, not recruiting NCT04308590 - Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas Phase 3
Recruiting NCT04127552 - Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations
Recruiting NCT05255900 - Effects of Metyrapone in Patients With Hypercortisolism
Recruiting NCT05766085 - Cortisol Secretion, Sensitivity and Activity and Hypertension