Hyperalgesia Clinical Trial
Verified date | June 2010 |
Source | Yonsei University |
Contact | n/a |
Is FDA regulated | No |
Health authority | Korea: Food and Drug Administration |
Study type | Interventional |
The purpose of this study is to study the effect of intraoperative magnesium on remifentanil-induced postoperative hyperalgesia after thyroidectomy
Status | Completed |
Enrollment | 84 |
Est. completion date | January 2010 |
Est. primary completion date | January 2010 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 20 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Patients undergoing thyroidectomy, - Age 20-65, - American Society of Anesthesiologists physical status classification I or II. Exclusion Criteria: - History of chronic pain, Regular use of analgesic, antiepileptic or antidepressive drugs, - History of drug & alcohol abuse, - Psychiatric disorder, - Use of opioids within 24hrs, - Renal disease with decreased GFR, - Neuromuscular disease, Severe cardiac disease. |
Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Severance Hospital | Seoul |
Lead Sponsor | Collaborator |
---|---|
Yonsei University |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Tactile pain thresholds adjacent to the surgical wound assessed by von Frey hair before the induction and at postoperative 24 & 48 hrs | postoperative 48 hrs | No |
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