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Hyaluronic Acid clinical trials

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NCT ID: NCT05935501 Completed - Hyaluronic Acid Clinical Trials

Clinical Trial of Cross-linked Hyaluronic Acid Dermal Filler

Start date: August 27, 2018
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Young Dermal Filler Injection, which is a hyaluronic acid dermal filler injected into the mid to deep dermis for the correction of moderate-to-severe nasolabial fold facial wrinkles. The main questions it aims to answer are: - The differences of Wrinkle Severity Rating Scale (WSRS) after the injection. - The treatment improvement assessed by Global Aesthetic Improvement Scale (GAIS). - Safety Indicators of which incidences on the day of the injection or after the injection. Participants will be blinded and randomized into either experiment group or control group, and re-visited on 1, 3, 6, 9 and 12 month after injection. Researchers will compare if the test product is non-inferiority to Restylane.

NCT ID: NCT05935449 Completed - Lidocaine Clinical Trials

The Clinical Trial of Difference Between Formaderm Lidocaine and Formaderm Dermal Filler Injection

Start date: August 4, 2020
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Lidocaine to the correction of nasolabial folds wrinkle and reduction of pain immediately after treatment. The main questions it aims to answer are: 1. The pain score assessed using Visual Analog Pain Scale(VAS) and Thermometer Pain Scale(TPS). 2. The facial wrinkle assessed using Wrinkle Severity Rating Scales(WSRS). 3. The treatment improvement assessed using Global Aesthetic Improvement Scale (GAIS). 4. Safety Indicators of which incidences on the day of the injection or after the injection. Participants will be self-controlled and randomized for same period, - received both trial product and control product at the same time. - re-visited on Day 14 and Day 30 after injection. The researchers will compare whether Formaderm Lidocaine is superior to Formaderm Dermal Filler Injection (without lidocaine) in terms of pain relief experienced by subjects during injection.

NCT ID: NCT05881330 Completed - Hyaluronic Acid Clinical Trials

ArtiAid® for Knee Osteoarthritis: A Post-market Study

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

The goal of this open-label, post-market clinical follow-up study is to demonstrate the safety and performance of ArtiAid® Intra-articular Injection in patients with knee osteoarthritis(OA). The main questions it aims to answer are: - the safety profile of ArtiAid®; - the clinical performance of ArtiAid®, such as pain relief and satisfaction of treatment. Participants will receive weekly injections of ArtiAid® for 5 weeks and be follow-up for 26 weeks.

NCT ID: NCT05881317 Completed - Hyaluronic Acid Clinical Trials

ArtiAid® Plus for Knee Osteoarthritis: A Post-market Study

Start date: August 2, 2021
Phase: N/A
Study type: Interventional

The goal of this open-label, post-market clinical follow-up study is to demonstrate the safety and performance of ArtiAid® Plus Intra-articular Injection in patients with knee osteoarthritis(OA). The main questions it aims to answer are: - the safety profile of ArtiAid® Plus; - the clinical performance of ArtiAid® Plus, such as pain relief and satisfaction of treatment. Participants will receive weekly injections of ArtiAid® Plus for 3 weeks and be follow-up for 26 weeks.

NCT ID: NCT05294562 Completed - Hyaluronic Acid Clinical Trials

China Post-Market Clinical Follow-up of FACILLE®

Start date: December 14, 2016
Phase:
Study type: Observational

The results showed that subjects tolerated the Sodium Hyaluronate Gel for Injection (FACILLE®) well, with no systemic AEs, SAEs, and unanticipated AEs and associated with high satisfaction and self-evaluated effectiveness. Nearly half of the subjects maintained correction for 12 months and were satisfied with the product 3 years after the first injection.

NCT ID: NCT05201040 Completed - Knee Osteoarthritis Clinical Trials

Evaluate the Safety and Effectiveness of Mannitol-combined Hyaluronan Supplement in the Treatment of Knee OA

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of JETKNEE Synovial Fluid Supplement for alleviating pain of knee osteoarthritis (OA).

NCT ID: NCT04865952 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

NCT ID: NCT04812457 Completed - Hyaluronic Acid Clinical Trials

Hyaluronic Acid in Postoperative Cures in the Phenol/Alcohol Technique

EHAPAT
Start date: March 6, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to compare the efficacy of a postoperative treatment protocol with hyaluronic acid-based ointment compared to the standard protocol (betadine gel) in partial chemical matricectomies with phenol alcohol technique. This will allow to see if the use of hyaluronic acid could help to reduce the healing time and total recovery of this surgical technique

NCT ID: NCT04622085 Completed - Lidocaine Clinical Trials

The Evaluation of the Safety and Effectiveness of ANIMERS Chiara LA and JUVÉDERM VOLUMA® for Aging Mid-Face

Start date: April 6, 2021
Phase: N/A
Study type: Interventional

This study is to evaluate the safety and effectiveness for the correction of aging mid-face of treatment group compared with the active control group.

NCT ID: NCT04599335 Completed - Lidocaine Clinical Trials

The Evaluation of the Safety and Effectiveness of a Novel Gel-type Sodium Hyaluronate for the Correction of Aging Mid-face

Start date: April 6, 2021
Phase: N/A
Study type: Interventional

This study is to evaluate the safety and effectiveness for the correction of aging mid-face of treatment group compared with the negative control group.