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Human Milk clinical trials

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NCT ID: NCT03001479 Completed - Clinical trials for Premature Birth of Newborn

Noninferiority Trial of Liquid Human Milk Fortifier (HMF) Hydrolyzed Protein Versus Liquid HMF With Supplemental Liquid Protein

Start date: March 13, 2017
Phase: N/A
Study type: Interventional

Breast milk is readily accepted as the ideal source of nutrition for almost all infants, including premature or very low birth weight infants. However, these high-risk infants require the addition of fortifiers to their milk in order to achieve sufficient levels of calories, vitamins, and minerals for adequate growth. We are currently using a liquid human milk fortifier which does not provide sufficient protein intake, requiring addition of a liquid protein supplement. A new product has been released which provides sufficient protein in the liquid HMF, without the acidification seen in previous products. This is a prospective, randomized noninferiority study comparing the safety and efficacy of the new HMF with additional protein to our current standard of adding additional protein supplementation on top of the HMF.

NCT ID: NCT02133716 Completed - Pain Clinical Trials

Efficacy of Breast Milk Expressed and Sucrose in Procedural Pain in Preterm

LACTEET
Start date: October 2013
Phase: Phase 4
Study type: Interventional

The aim of this study is to assess the non-inferiority of non- pharmacological breast milk expressed versus oral sucrose in relief procedural pain of venipuncture in preterm neonates. This is an experimental comparative study of non-inferiority randomized crossover, to be performed in Neonatal units of hospitals in the Community of Madrid. The 54 pair of preterm that after the selection criteria are included in the study, they performed the randomization of the sequence and breast milk expressed receive oral or 24% sucrose. The doses administered are: 0.1ml preterm less than 27 weeks corrected gestational age (CGA), 0.25 ml for infants 27 to 31 weeks CGA and 0.5 ml for infants of 32-37 weeks. Both groups will be accompanied by non-nutritive sucking and swaddling and administered two minutes prior to venipuncture. The outcome variable, pain, will be determined by the scale Premature Infant Pain Profile (PIPP) and by percent of cry. Data for the primary objective was analysed per intention to treat. This study was approved by local ethical committee.

NCT ID: NCT01988792 Completed - Enteral Nutrition Clinical Trials

Human Milk Fortification in Very Low Birth Neonates

Start date: November 2013
Phase: N/A
Study type: Interventional

The purpose of this study to find out how safely we can add extra nutrients to human milk at different feeding volume.

NCT ID: NCT01932619 Completed - Human Milk Clinical Trials

The Influence of Storage Container and Defrost Process on Components in Breast Milk

Start date: January 2009
Phase: N/A
Study type: Observational

Breast milk is best food for neonates and preterm infants. However many handling would be done if direct breastfeeding is not feasible, and it may result in nutrients change in human milk. We investigate the influence of storage in different containers and different thawing or heating methods on human milk nutrients.