HIV Clinical Trial
Official title:
5 Years Follow-up Evaluation of Deterioration Kidney Biomarkers of HIV Patients : HIVOL 2 Study.
The aim of this study is to compare the biomarkers levels as IL-18, KIM-1 and Cystatin C for patients infected by HIV with failure in renal function at year 5. The main criterion will be a degradation of the glomerular filtration throughput measured. It will be compared to clinical scores of degradation risks of renal function for patients infected with HIV.
The aim of this study is to compare the biomarkers levels as IL-18, KIM-1 and Cystatin C for
patients infected by HIV with failure in renal function at year 5. The main criterion will be
a degradation of the glomerular filtration throughput measured. It will be compared to
clinical scores of degradation risks of renal function for patients infected with HIV.
From 2011 to 2013, researchers realized a study called HIVOL, on the diagnostic performance
of GFR (Glomerular Filtration Rate) estimators in patients infected with HIV. It lead to a
publication in AIDS, retaken in the rational of recommendations of Infectious Diseases
Society of America for the Chronic Renal Diseases support for patients infected with HIV.
235 patients were involved, for everyone researchers have a GFR measure (by Iohexol plasmatic
clearance) and urinary and plasma samples.
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