Depression Amongst HIV Positive Patients in Lilongwe

HIV Clinical Trial

Official title:

Prevalence of Depression Amongst HIV Positive Patients Attending ART Clinic at Lighthouse Clinic, Lilongwe

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02646605
• Other study ID #: 12-2158
• Status: Completed
• Phase: N/A
• First received: January 4, 2016
• Last updated: January 4, 2016
• Start date: May 2013
• Est. completion date: September 2013

Study information

• Verified date: January 2016
• Source: University of North Carolina, Chapel Hill
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review BoardMalawi: National Health Sciences Research Committee
• Study type: Observational

Clinical Trial Summary

Quantitative, validated tools of depression screening will be used to collect data to determine the prevalence of depression and its association with antiretroviral (ARV) adherence amongst HIV positive patients attending ART clinic at Lighthouse Lilongwe, Malawi.

Description:

Preliminary data on prevalence and associations will be collected from 200 HIV positive adult men and women attending ART clinic at the Lighthouse in Lilongwe, Malawi. Quantitative, validated tools of depression screening will be used. A short structured demographic questionnaire will be used to collect demographic data. For depression, a Patient Health Questionnaire (PHQ) will be used while alcohol use will be assessed by Alcohol Use Disorders Identification Test (AUDIT) screening tool. The data collected will provide baseline data planning, program development and evaluation, and to promote comprehensive care provision for the people living with AIDS attending ART clinics in Malawi.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 206
• Est. completion date: September 2013
• Est. primary completion date: September 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years and above

• HIV positive men and women accessing care at LH

• Both ART naïve and on ART

• Registered with LH

• Receiving primary care and/ or ART from LH

Exclusion Criteria:

• Too sick to comprehend consent or requiring admission

• Known mentally ill patient on psychiatric drugs

• Less than 18 years old

Study Design

Observational Model: Case-Only, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

• AIDS
• HIV

Intervention

Other:
• depression screening
Patient Health Questionnaire

Locations

Country	Name	City	State
Malawi	Lighthouse Clinic	Lilongwe

Sponsors (2)

Lead Sponsor	Collaborator
University of North Carolina, Chapel Hill	Fogarty AIDS international training research program

Country where clinical trial is conducted

Malawi, 

References & Publications (5)

Guilbert JJ. The world health report 2002 - reducing risks, promoting healthy life. Educ Health (Abingdon). 2003 Jul;16(2):230. — View Citation

Malawi Demographic Profile 2012

Mwale M.C. et al (2006) The Prevalence Of Psychological Distress And Associated Factors Among People Living With Aids Attending Antiretroviral Therapy Clinics In Mzuzu, Malawi: A Cross Sectional Descriptive study. Accessed on 09 June 2012 from www.medcol.mw/mph/.../Charles%20M%20%20Mwale.pdf

Rochon PA, Mashari A, Cohen A, Misra A, Laxer D, Streiner DL, Dergal JM, Clark JP, Gold J, Binns MA. Relation between randomized controlled trials published in leading general medical journals and the global burden of disease. CMAJ. 2004 May 25;170(11):1673-7. — View Citation

World Health Organisation. (2005). Promoting Mental Health: concepts, emerging evidence, practice: report of the world health organisation, Dept of Mental Health and Substance Abuse in collaboration with the Victorian Health Promotion Foundation & the University of Melbourne. Geneva: World Health Organisation.

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of depression amongst HIV positive patients attending ART clinic at Lighthouse Lilongwe, Malawi	the survey will be administered one time	enrollment	No