Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
FMRI images will be performed for changes in the brain between the groups |
Cerebral metabolite abnormalities |
Baseline and 6 month follow-up |
|
Secondary |
Structured Clinical Interview for Diagnostic and Statistical Manual (DSM)-IV (SCID) |
A structured interview given to participants in order to assess current and past alcohol use and dependence |
Baseline |
|
Secondary |
Lifetime Alcohol and Drug Use History |
This interview will be conducted at baseline to gather information about age of onset of alcohol use, period of heaviest drinking, most drinks consumed on a single day, and number of drug classes used lifetime. |
Baseline |
|
Secondary |
Kreek-McHugh-Schluger-Kellogg (KMSK) Scale |
Developed as a research measure of drug use severity in accordance with DSM-IV criteria, the KMSK is reliable and valid, quantifying frequency, duration, and amount of individual drug use. |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Timeline Followback (TLFB) |
The TLFB interview will be used to assess recent alcohol use at baseline, as well as during the follow-up intervals. The TLFB interview is a calendar-assisted structured interview which provides a way to cue memory so that accurate recall is enhanced. The TLFB will provide data on the percentage of drinking days, drinks consumed per week, and the percentage of heavy drinking days. |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Urine Drug Screen |
Urine drug screens will be performed using Varian's TestCup Pro5, testing for benzodiazepines, amphetamines, opiates, & cocaine. |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Short Inventory of Problems (SIP) |
The SIP assesses 15 negative consequences of alcohol use over the chosen time period (in this case 3 months) and has been found to have good psychometric properties. Maximum score is 45 |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Epworth Sleepiness Scale (ESS) |
The ESS proposes eight daytime scenarios, and the participant is asked to rate how likely they are to fall asleep in each situation on a four-point scale (0-3). |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Center for Epidemiological Studies-Depression Scale (CES-D) |
A 20-item screening test for depression and depressive disorder |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Beck Anxiety Inventory |
21-question multiple-choice self-report inventory that is used for measuring the severity of anxiety |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Early Life Stress Questionnaire (ELSQ) |
A 5-section self-report questionnaire assessment of adverse childhood events |
Baseline |
|
Secondary |
The Frontal System Behavioral Scale (FrSBe) |
A 46-item self-report questionnaire designed to measure behavior related to frontal systems damage |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Medical Outcomes Study HIV Health Survey (MOS-HIV) |
A 35-item self-report questionnaire designed in order to assess functional status and well-being among HIV-positive individuals |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Montreal Cognitive Assessment (MoCA) |
measurement used to screen for dementia and mild cognitive impairment |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Hopkins Verelan Learning Test Revised (HVLT-R) |
cognitive assessment that measures verbal learning and memory |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Brief Visuospatial Memory Test Revised (BVMT-R) |
A measure of visuospatial memory |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Paced Auditory Serial Addition Test (PASAT-1) |
A cognitive assessment which measures visuospatial memory |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
WAIS-3 Letter Number Sequencing |
7-item cognitive assessment with a total of 21 maximum points |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
WAIS-3 Digit Symbol |
A timed neuropsychological test sensitive to brain damage, dementia, age and depression consisting of digit-symbol pairs followed by a list of digits |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
WAIS-3 Symbol Search |
Cognitive assessment measuring processing speed with a total max score of |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Trail Making |
timed cognitive assessment looking at working memory and executive functioning |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Grooved Pegboard |
measures performance speed in a fine motor task |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Stroop Task |
timed cognitive task |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Verbal Fluency |
timed language measure |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Animal Fluency |
timed language measure |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
The Wechsler Test of Adult Reading (WTAR) |
cognitive tast measuring verbal intelligence |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Boston Naming Test |
|
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
Adaptive Rate Continuous Performance Test (ARCPT) |
computerized adaptive task measuring attention |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|
Secondary |
California Computerized Assessment Package (CalCAP) |
computerized task measuring reaction time |
Baseline, 3-month, 6-month, and 12-month follow-ups. |
|