HIV Clinical Trial
Official title:
Randomized Controlled Trial of Situated Optimal Adherence Intervention Estonia (sOAI Estonia) Among Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia
The specific aim of the study is to assess antiretroviral therapy adherence and evaluate the impact of a situated treatment adherence intervention program among persons living with HIV/AIDS on antiretroviral therapy in Estonia.
Specific antiretroviral therapy (ART) can suppress HIV replication and consequently preserve
the functioning of immune system. ART is a lifelong treatment with several different
concomitantly administered oral medications. According to studies, low adherence to
treatment is directly related to knowledge and beliefs about ART.
Studies have shown the success of different interventions increasing adherence to ART, but
additional studies need to be carried out in order to determine the most effective
components of the interventions and the methods most suitable considering the local context,
that could be easily incorporated into the working routine of an medical institution
(clinic) with limited extra resources.
Primary locations to implement activities directed at improving treatment adherence are
medical institutions, i.e. the departments of infectious diseases where persons living with
HIV/AIDS receive their ART.
The aim of the study is to conduct a small-scale intervention (randomised controlled) study
implementing a brief adherence counseling targeting persons receiving ART.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Supportive Care
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