HIV Clinical Trial - NRTI-Sparing Pilot Study

Status Completed

Clinical Trial Summary

This study will compare a nucleoside reverse transcriptase inhibitor-sparing (NRTI-sparing) regimen (Kaletra + nevirapine) to two nucleoside reverse transcriptase inhibitor-based regimens (Combivir + nevirapine and Combivir + Kaletra).

Participants will be randomly assigned to receive one of the following drug combinations:

- lopinavir/ritonavir (Kaletra) and nevirapine (Viramune) twice a day;

- Combivir (Zidovudine (AZT) plus lamivudine (3TC)) and nevirapine twice a day;

- Combivir and lopinavir/ritonavir twice a day.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00143689
Study type	Interventional
Source	University of British Columbia
Contact
Status	Completed
Phase	Phase 4
Start date	April 2002
Completion date	February 2008

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