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Clinical Trial Summary

Co-morbidities, including low bone mineral density, increased visceral adiposity and chronic kidney disease (CKD) are frequent in people living with HIV, and may be driven by ongoing inflammation and immune activation. Initiation of ART reduces inflammation and immune activation and is associated with changes in bone and renal biomarkers and gut microbiota. Investigators hypothesise that changes in gut microbiome when starting antiretroviral therapy correlate to changes in bone and renal biomarkers and wish to explore possible mechanisms linking these by investigating changes in markers of inflammation and immune activation.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03660722
Study type Interventional
Source Centre Hospitalier Universitaire de Saint Etienne
Contact
Status Withdrawn
Phase N/A
Start date October 2023
Completion date February 2024

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